Results 41 to 50 of about 596 (140)
Discovery of a isothiazolinone-containing antitubercular natural product levesquamide
, 2020 Antitubercular agent levesquamide is a new polyketide-nonribosomal peptide (PK-NRP) hybrid marine natural product isolated from Streptomyces sp. RKND-216. The structure contains a rare isothiazolinone moiety which has only been reported in collismycin SN.
core +1 more source
Contact Dermatitis, EarlyView.This study identified multiple areas for improvement in the regulatory risk assessment process. Conclusions based on predictive sensitization data should be made with caution, read‐across data from known sensitizers should be utilized, and epidemiological and patient threshold data should be prioritized in decision‐making.
Mathias Krogh Pedersen +7 more
wiley +1 more source
Environment International, 2022 A variety of isothiazolinone-containing small molecules have been registered and used as chemical additives in many household products. However, their biodistribution and potential harmful effects on human health, especially respiratory effects, were not
Mi-Kyung Song +9 more
doaj +1 more source
Effect of Cosmetics Use on the In Vitro Skin Absorption of a Biocide, 1,2-Benzisothiazolin-3-one
Toxics, 2022 1,2-Benzisothiazolin-3-one (BIT) is a commonly used organic biocide containing an isothiazolone ring. However, it may have adverse effects on human health and its risk needs to be properly evaluated. Dermal exposure is the main route of BIT exposure, and
Yoonjung Huh +3 more
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Contact Dermatitis, EarlyView.ABSTRACT Background Over‐ear headphones are a growing source of allergic contact dermatitis (ACD). Identifying well‐known and new culprit sensitizers in such products is challenging because of a lack of labelling and limited cooperation from manufacturers.
Goël Fenech +5 more
wiley +1 more source
Contact Dermatitis, Volume 95, Issue 4, Page 405-412, October 2026.MCI/MI and MI contact allergy remain persistent. In this analysis of the Danish market, 257 products containing MCI/MI or MI were identified, and 30 products were analysed. Two exceeded regulatory limits, while most complied, suggesting current limits may require further investigation. Created in BioRender. Pedersen, M. K.
Mathias Krogh Pedersen +9 more
wiley +1 more source
"Application effects of isothiazolinone preservatives in carboxyl nitrile rubber latex"
Hecheng xiangjiao gongyeBy detecting the microbial growth of carboxyl nitrile rubber latex and residual amount of preservatives, it was found that under high temperature by seaborne, the preservative Kathon (usually the mass ratio of active ingredient chloromethyliso ...
ZHANG Jin
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, 2021 Changes in the physical state of the cells can serve as important indicators of stress responses because they are closely linked with the changes in the pathophysiological functions of the cells.
Choi, Jinhee +7 more
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Contact Dermatitis, Volume 95, Issue 3, Page 286-294, September 2026.In this exploratory analysis, dyshidrotic eczema demonstrated a distinct sensitisation pattern compared with non‐dyshidrotic hand eczema. The lower proportion of clinically relevant reactions amongst positive patch tests suggests a multi‐factorial and not exclusively allergic background.
Araceli Sánchez‐Gilo +28 more
wiley +1 more source
World Allergy Organization Journal, 2020 Background: It is estimated that 20% of the general population is sensitized to some kind of contact allergen. Contact dermatitis is one of the major occupational diseases worldwide.
Giovanni Sedó-Mejía +4 more
doaj +1 more source