Results 131 to 140 of about 100,704 (351)

Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation

Advanced Science, EarlyView.
BPB (Bisphenol B) exposure up‐regulates ER (estrogen receptor) levels, enhances its interactions with the lnc‐HZ04 promoter region, and thus promotes ER‐mediated lnc‐HZ04 transcription. Subsequently, lnc‐HZ04 suppresses TCF4 (transcription factor 4)‐mediated PKCA (protein kinase C alpha) transcription and subsequently suppresses migration/invasion and ...
Wenxin Huang, Manli Wang, Yi Sun, Xiaoping Yue, Xun Li, Yanbing Lin, Geng Guo, Depeng Zhao, Qigang Fan, Xiaoling Ma, Zhihong Zhang, Shuaishuai Xing, Xiaoting Shen, Huidong Zhang   +13 more
wiley   +1 more source

Symbiodiniaceae and Ruegeria sp. Co-Cultivation to Enhance Nutrient Exchanges in Coral Holobiont

Microorganisms
The symbiotic relationship between corals and their associated microorganisms is crucial for the health of coral reef eco-environmental systems. Recently, there has been a growing interest in unraveling how the manipulation of symbiont nutrient cycling ...
Yawen Liu, Huan Wu, Yang Shu, Yanying Hua, Pengcheng Fu   +4 more
doaj   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Ratoon Season Rice Reduces Methane Emissions by Limiting Acetic Acid Transport to the Rhizosphere and Inhibiting Methanogens

Advanced Science, EarlyView.
This study finds that the interaction between ABA‐OsCIPK2‐OsSWEET1A reduces the allocation of methane producing bacteria carbon source (acetic acid) content to the rhizosphere soil of ratoon season rice, thereby reducing methane emissions. Abstract Rice paddies are a major, persistent source of atmospheric methane (CH4), emission rates depend on the ...
Jingnan Zou, Hailong Xu, Bin Qin, Chaojie Lan, Jinying Li, Bianhong Zhang, Huabin Zhang, Chunlin Guo, Hongfei Chen, Zhongming Fang, Quanzhi Zhao, Wenfei Wang, Changxun Fang, Zhixing Zhang, Wenxiong Lin   +14 more
wiley   +1 more source

stable isotope labelling

Citation: 'stable isotope labelling' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09782 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

An ANGPTL4-ceramide-protein kinase Cζ axis mediates chronic glucocorticoid exposure-induced hepatic steatosis and hypertriglyceridemia in mice. [PDF]

, 2019
Chronic or excess glucocorticoid exposure causes lipid disorders such as hypertriglyceridemia and hepatic steatosis. Angptl4 (angiopoietin-like 4), a primary target gene of the glucocorticoid receptor in hepatocytes and adipocytes, is required for ...
Cheang, Rachel T, Chen, Tzu-Chieh, Fitch, Mark D, Gray, Nora E, Hellerstein, Marc K, Kanamaluru, Deepthi, Lee, Justin Y, Lee, Rebecca A, Tan, Jenna H, Tsai, Sam L, Wang, Jen-Chywan, Yiv, Nicholas   +11 more
core  

Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells

Advanced Science, EarlyView.
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha, Benjamin Yang, Dongqiang Yuan, Edmund D. Kapelczak, Philip A. Kocheril, Alonso Tapia, Shivansh Mahajan, Adrian Colazo, Naseeb K. Malhi, Joseph A. Ambarian, Xuejing Liu, Tara A. TeSlaa, Zhen B. Chen, Lu Wei   +13 more
wiley   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Quantitative plant proteomics using hydroponic isotope labeling of entire plants (HILEP) [PDF]

, 2011
A. Gruhler, A. Keller, A. Keller, A. Kolkman, A. Panchaud, A. Ross, A. Schmidt, A.I. Nesvizhskii, A.J. Heck, C.C. Wu, C.J. Nelson, D. Hoagland, D. Huttner, D.K. Han, E.C. Yi, E.L. Huttlin, F.A. Kaffarnik, G. Wang, H. Noren, J. Krijgsveld, J. Zhai, J.B. Jones, J.C. Silva, J.E. Schaff, J.F. Timms, J.H. Ippel, J.J. Benschop, J.J. Thelen, J.P. Whitelegge, L. Dayon, L.N. Mueller, L.V. Bindschedler, M. Mann, M. Palmblad, M. Palmblad, M. Palmblad, M. Unlu, M.A. Hughes, M.J. MacCoss, P. Ross, P.J. Boersema, P.L. Ross, R. Hebeler, R. Marouga, S. Oeljeklaus, S.E. Ong, T.P. Conrads, W.R. Engelsberger, X. Yao, Y. Ishihama, Y. Zhang   +50 more
core   +1 more source