Results 191 to 200 of about 100,704 (351)

THU0104 HIGH-PERFORMANCE CHEMICAL ISOTOPE LABELING LIQUID CHROMATOGRAPHY MASS SPECTROMETRY FOR DISCOVERY OF METABOLITE BIOMARKERS OF RHEUMATOID ARTHRITIS [PDF]

, 2019
Xiaohang Wang, Joel Paschke, R. Dadashova, Edna Hutchings, Li Liang, Walter P. Maksymowych   +5 more
openalex   +1 more source

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

Advanced Science, EarlyView.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen, Rong‐Xin Zhu, Nuo‐Xi Zhang, Ting‐Ting Sun, Xi‐Wei Zhang, Yu‐Jie Zhao, Ben‐Yu He, Hang Yao, Ren‐Hong Du, Lei Cao, Wen‐Bin Zhang, Wei‐Guo Liu, Yun Cai, Cong Wang, Gang Hu, Yao Wei, Yang Liu, Ming Lu   +17 more
wiley   +1 more source

Scaling up the production of fungal perylenequinones and investigating their biosynthesis through stable isotope labeling. [PDF]

Microb Cell Fact
Al-Qiam RA, Dumbare S, Graf TN, Vidar WS, Raja HA, Pearce CJ, Hematian S, Oberlies NH.   +7 more
europepmc   +1 more source

Stable isotope labeling as a promising tool for rapid drug susceptibility testing in Neisseria gonorrhoeae. [PDF]

Braz J Microbiol, 2023
Dadwal R, Paul S, Gupta P, Yadav R, Sood S, Ghosh AK, Shivaprakash MR, Gainder S, Sethi S.   +8 more
europepmc   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source

A Comparative Metabolomics Study of Multiple Urological Diseases by Highly Sensitive Dansylation Isotope Labeling LC-MS. [PDF]

Int J Mol Sci
Wang WH, Hsieh YJ, Chen CL, Chang YH, Tsai YH, Chang CH, Li L, Tu WJ, Yu JS, Chen YT.   +9 more
europepmc   +1 more source

Probing local changes to α-helical structures with 2D IR spectroscopy and isotope labeling. [PDF]

Biophys J, 2023
Webb KR, Hess KA, Shmidt A, Segner KD, Buchanan LE.   +4 more
europepmc   +1 more source

Determining N supplied sources and N use efficiency for peanut under applications of four forms of N fertilizers labeled by isotope 15N

, 2016
Wang Cai-bin, Zheng YongMei, Pu Shen, Zheng Yaping, Zhengfeng Wu, Xuewu Sun, Tianyi Yu, Hao Feng   +7 more
openalex   +1 more source

ENDOR spectroscopy of chlorophylls and the photosynthetic light conversion apparatus [PDF]

, 1979
Dolphin, D., Katz, Joseph J., Norris, James R., Scheer, Hugo   +3 more
core   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source