Results 71 to 80 of about 57,188 (237)

A Perspective on the Applications of Triphasic Gas Storage in Electrochemical Systems

open access: yesAdvanced Science, EarlyView.
Gas storage in microporous materials positioned locally at an electrode or electrocatalyst surface enhances electrochemical processes. Abstract Microporous materials store gases under dry conditions (e.g., hydrogen or oxygen via physisorption), but in some cases microporous materials also show triphasic (e.g., in a solid|gas|liquid system) gas storage ...
Zhongkai Li   +9 more
wiley   +1 more source

Progress and Application of Mass Spectrometry Techniques for Single Particle Analysis in Nuclear Safeguard

open access: yesZhipu Xuebao
The nuclear Non-proliferation Treaty (NPT) is one of the cornerstones regulating the international order. To make sure that all the member states fulfill their obligation under the treaty, the International Atomic Energy Agency (IAEA) has constructed a ...
Li-ping WANG   +5 more
doaj   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

open access: yesAdvanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang   +16 more
wiley   +1 more source

Stable carbon isotope discrimination by human 3-hydroxy-3-methylglutaryl-coenzyme A reductase

open access: yesJournal of Lipid Research, 2008
The aim of this study was to investigate the possible existence and magnitude of stable carbon isotope discrimination by human 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR). The catalytic portion of HMGR was expressed and purified.
Svena M. Lüdke   +3 more
doaj   +1 more source

Heme‐NO Dilates Arteries via Mobilization of NO Moieties From an Intracellular NO Store Within Vascular Smooth Muscle Cells

open access: yesAdvanced Science, EarlyView.
Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu   +9 more
wiley   +1 more source

Perspectives for the Study of 18O Isotope Effects of Enzymatic Phosphoryl Transfer Reactions by ESI-Orbitrap MS

open access: yesCHIMIA
Isotope effects play an important role in investigating enzymatic phosphoryl transfer reactions, which are central in biochemical pathways and environmental metabolism. However, resolving different isotope effects for mechanistic insights into phosphoryl
Nora M. Bernet, Thomas B. Hofstetter
doaj   +1 more source

Effect of Organic Matter in Water Samples on the Hydrogen Stable Isotope Ratio Determination by Thermal Conversion/Elemental Analysis-Isotope Ratio Mass Spectrometry

open access: yesYankuang ceshi, 2019
BACKGROUND In the study of hydrology and water resources, the hydrogen stable isotope ratio (δ2H) of water is an important detection parameter, and its changing patterns can be used to identify and quantify the source of water, and reveal the evolution ...
HAO Xin-li   +5 more
doaj   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

Isotope Mass Spectrometry in Meat Identification

open access: yesТехника и технология пищевых производств
Meat and meat products are consumed by a large proportion of the population. As a result, food scientists keep inventing new methods for meat identification, e.g., isotope mass spectrometry.
Lisitsyn Andrey   +5 more
doaj   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy