Results 141 to 150 of about 731,514 (328)
Assay of Isotopic Nitrogen by Mass-Spectrometer [PDF]
, 1958 A. P. Sims, E. C. Cocking
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Advanced Science, EarlyView.The globular shape and hydrophobicity of zein made it unsuitable to be processed in pure aqueous environment. Pepsin‐mediated hydrolysis converts zein into water‐soluble and fibril‐forming peptides with a bioconversion rate exceeding 70%, enabling the self‐assembly of amyloid‐like nanofibrils.
Mingqin Li +8 more
wiley +1 more source
Uranbestimmungen an Steinmeteoriten mittels Neutronenaktivierung über die Xenon-Isotope 133 und 135 [PDF]
, 1959 Hans‐Joachim König, H. Wänke
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Advanced Science, EarlyView.TRIM25‐mediated ubiquitination of INSIG1 serves as a key driver of lipid metabolism dysregulation in MASH progression. It identifies a novel small‐molecule inhibitor, C27H26N2O4S, which effectively inhibits TRIM25 activity, reducing lipid accumulation and inflammation.
Hao Zhang +8 more
wiley +1 more source
Advanced Science, EarlyView.Novel carbon‐11 labeled pyrimidine derivatives are developed as PET imaging probes for visualizing sigma‐1 receptors in the brain. [11C]CNY‐01 demonstrates superior brain uptake and binding specificity in both rodents and non‐human primates. The study reveals decreased sigma‐1 receptor expression in Alzheimer's disease, offering a promising tool for ...
Ping Bai +12 more
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Isotope Effect in the Thermal Cracking of Propane−1-C13 [PDF]
, 1948 D. P. Stevenson +3 more
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Advanced Science, EarlyView.Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi +20 more
wiley +1 more source
THE BIOGENESIS OF ALKALOIDS: III. A STUDY OF HYOSCYAMINE BIOSYNTHESIS USING ISOTOPIC PUTRESCINE [PDF]
, 1951 D. G. M. Diaper +2 more
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Advanced Science, EarlyView.This study investigates the integrated diagnostic and therapeutic strategy utilizing 89Zr/131I‐labeled tinurilimab for the management of malignant lung nodules, with a particular focus on lung adenocarcinoma (LUAD). CEACAM6, which is highly expressed in most LUAD patients, activates the Src/FAK signaling pathway, thereby promoting cell proliferation ...
Chongyang Chen +8 more
wiley +1 more source
Final-state rescattering mechanism of charmed baryon decays
Journal of High Energy PhysicsThe dynamical studies on the non-leptonic weak decays of charmed baryons are always challenging, due to the large non-perturbative contributions at the charm scale. In this work, we develop the final-state rescattering mechanism to study the two-body non-
Cai-Ping Jia +3 more
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