Results 211 to 220 of about 792,425 (354)

Revealing the Mechanism of Exciton Spontaneous Separation at Room Temperature for Efficient Photocatalytic Hydrogen Peroxide Synthesis

open access: yesAdvanced Science, EarlyView.
This study identifies that replacing electron‐donating units at different positions enhances the delocalization of the electron cloud in the electron donors, which in turn increases the delocalization of the overall material. The exciton activation energy is effectively reduced, promoting the spontaneous dissociation of excitons at room temperature and
Pan Jiang   +9 more
wiley   +1 more source

Amyloid Forming Human Lysozyme Intermediates are Stabilized by Non‐Native Amide‐π Interactions

open access: yesAdvanced Science, EarlyView.
Mutational variants of human lysozyme cause fatal systemic amyloidosis by depositing kilograms of protein in the viscera of patients. Central to this process is a partially unfolded protein intermediate state that initiates aggregation into amyloid fibrils.
Minkoo Ahn   +6 more
wiley   +1 more source

Sequence‐ and Docking‐Site‐Dependent Contributions to Multi‐Site Phosphorylation of an Intrinsically Disordered MAPK Substrate

open access: yesAdvanced Science, EarlyView.
Real‐time NMR spectroscopy is used to study JNK1‐dependent phosphorylation of the intrinsically disordered substrate JIP1, revealing eleven phosphosites with distinct phosphorylation efficiencies. The site‐specific phosphorylation rates are shown to be determined by both the sequence position of the phosphosites relative to the two kinase docking site ...
Thibault Orand   +7 more
wiley   +1 more source

Single-Pulse Response LA-ICP-MS Imaging with Quadrupole Instrumentation: Theoretical Considerations and Practical Assessment. [PDF]

open access: yesAnal Chem
Willner J   +6 more
europepmc   +1 more source

DeepSecMS Advances DIA‐Based Selenoproteome Profiling Through Cys‐to‐Sec Proxy Training

open access: yesAdvanced Science, EarlyView.
DeepSecMS, a deep learning platform leveraging a Cys‐to‐Sec proxy training strategy, enhances the identification of known selenoproteins and holds promise for discovering novel candidates. This proxy approach overcomes limitations associated with the rarity of known selenoproteins and demonstrates broad applicability in studying other rare protein ...
Chenfang Si   +5 more
wiley   +1 more source

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