Results 91 to 100 of about 25,952 (244)

Correlated isotopic and microstructural studies of turbostratic presolar graphites from the Murchison meteorite

, 2008
We present data from TEM and NanoSIMS investigations of Murchison (CM2) KFC1 presolar graphites. TEM examinations of graphite ultramicrotome sections reveal varying degrees of graphite disorder, leading to distinctions between well-graphitized onions ...
BERNATOWICZ, T. J., STADERMANN, F. J., CROAT, T. K.   +2 more
core   +2 more sources

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Geochemistry and origin of the Asimotrypes carbonate hosted mesothermal gold deposit, Pangeon mountain, N. Greece

, 2000
The Asimotrypes mesothermal gold deposit located in the Pangeon Mt (E. Macedonia, N. Greece), is part of the Western Rhodope Massif (WRM), which represents the metamorphic core complex of an alpine collision orogen. Alpine metamorphism, of U. Cretaceous -
Eliopoulos, Demetrios G.
core  

Quantitative Structural Constraints for Organic Powders at Natural Isotopic Abundance Using Dynamic Nuclear Polarization Solid-State NMR Spectroscopy

, 2015
International audienceA straightforward method is reported to quantitatively relate structural constraints based on 13C–13C double-quantum build-up curves obtained by dynamic nuclear polarization (DNP) solid-state NMR to the crystal structure of organic ...
Viel, Stéphane, Stéphane Viel, Dekhil, Myriam, Ziarelli, Fabio, Thureau, Pierre, Fabio Ziarelli, Myriam Dekhil, Giulia Mollica, Pierre Thureau, Mollica, Giulia   +9 more
core   +1 more source

Heme‐NO Dilates Arteries via Mobilization of NO Moieties From an Intracellular NO Store Within Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu, Meijuan Zhang, Lingchao Zhu, Haiyan Ke, Amancio de Souza, Qian Li, Daniel Castella, Nicolai Lehnert, Lubo Zhang, Arlin B. Blood   +9 more
wiley   +1 more source

The marine life of Atlantic salmon: evidence from the chemistry of scales [PDF]

, 2010
This research provides a new method to identify likely marine feeding grounds for migratory pelagic species that are problematic to directly study at sea.
MacKenzie, Kirsteen Morag
core  

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

A mechanism for the fractionation of isotopes in ³He-rich solar energetic particle events

, 2020
By employing our charge-consistent acceleration model we demonstrate a possibility to explain the isotopic ratios observed in a number of 3He-rich events.
Ostryakov, V., Kartavykh, Y., Dröge, W., Klecker, B., Kovaltsov, G.   +4 more
core   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source