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Reactions Weekly, 2020
Isotretinoin is chemically named as: (2Z, 4E, 6E, 8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenoic acid. It is an orally active retinoic acid derivative for the treatment of severe refractory nodulocystic acne. It acts primarily by reducing sebaceous gland size and sebum production, and as a result alters skin surface lipid ...
Nasr Y, Khalil +2 more
+5 more sources
Isotretinoin is chemically named as: (2Z, 4E, 6E, 8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenoic acid. It is an orally active retinoic acid derivative for the treatment of severe refractory nodulocystic acne. It acts primarily by reducing sebaceous gland size and sebum production, and as a result alters skin surface lipid ...
Nasr Y, Khalil +2 more
+5 more sources
Journal of the American Academy of Dermatology, 1984
Approximately 120,000 women of childbearing age used isotretinoin in the first 16 months after its release for the treatment of cystic acne. In September, 1983, the American Academy of Dermatology requested its members to relate the outcome of pregnancies of women inadvertently exposed to isotretinoin ( Accutane ) during pregnancy to its Adverse Drug ...
R S, Stern, F, Rosa, C, Baum
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Approximately 120,000 women of childbearing age used isotretinoin in the first 16 months after its release for the treatment of cystic acne. In September, 1983, the American Academy of Dermatology requested its members to relate the outcome of pregnancies of women inadvertently exposed to isotretinoin ( Accutane ) during pregnancy to its Adverse Drug ...
R S, Stern, F, Rosa, C, Baum
openaire +2 more sources
Isotretinoin as contraindication
BMJ, 2011We wish to raise awareness of a potential hazard of laser refractive surgery and concurrent treatment with isotretinoin, an anti-acne drug.1 Acne affects 85-90% of the population at some time, and the age of patients affected by acne overlaps that of patients undergoing laser-assisted in …
Moona, Malik +2 more
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Isotretinoin‐Induced Agranulocytosis
Pediatric Dermatology, 2007Abstract: Isotretinoin is used to treat a spectrum of dermatologic conditions. The present article reports the case of a 15‐year‐old female patient who exhibited agranulocytosis after the initiation of isotretinoin administration. Agranulocytosis is a rare but life‐threatening side effect of isotretinoin use, and clinicians must be aware of ...
Patiroglu, Türkan +5 more
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Drug Intelligence & Clinical Pharmacy, 1984
Isotretinoin is remarkably effective in the treatment of severe cystic acne, however, many complications have been observed during treatment and new toxic effects have been reported. Hypertriglyceridemia associated with decreases in high density lipoprotein (HDL) cholesterol has occurred in 25 percent of patients and requires monitoring during ...
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Isotretinoin is remarkably effective in the treatment of severe cystic acne, however, many complications have been observed during treatment and new toxic effects have been reported. Hypertriglyceridemia associated with decreases in high density lipoprotein (HDL) cholesterol has occurred in 25 percent of patients and requires monitoring during ...
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Archives of Dermatology, 1984
To the Editor.— The frequent use of isotretinoin (Accutane) reminds me of the adage when penicillin was first introduced: "If an injection of penicillin doesn't cure the condition it's advisable to examine the patient." The following anecdotal reports are limited and uncontrolled, but I wonder what a controlled objective report of isotretinoin ...
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To the Editor.— The frequent use of isotretinoin (Accutane) reminds me of the adage when penicillin was first introduced: "If an injection of penicillin doesn't cure the condition it's advisable to examine the patient." The following anecdotal reports are limited and uncontrolled, but I wonder what a controlled objective report of isotretinoin ...
openaire +2 more sources