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Isotretinoin Laboratory Monitoring in Acne Treatment: A Delphi Consensus Study.

JAMA dermatology, 2022
Importance Although isotretinoin may rarely be associated with laboratory abnormalities such as hypertriglyceridemia, the optimal approach to laboratory monitoring is uncertain, and there is wide variation in clinical practice. Objective To establish a
Eric Xia   +25 more
semanticscholar   +1 more source

Oral isotretinoin for acne: a complete overview

Expert Opinion on Drug Safety, 2022
Introduction Acne is one of the most common and widespread skin conditions, affecting the health as much as patients’ quality of life. A wide variety of treatments for acne, topical and systemics, could be prescribed, depending on its degree of severity.
A. Villani   +5 more
semanticscholar   +1 more source

Systemic isotretinoin has an impact on hemoglobin, ferritin, urea, ceruloplasmin, albumin, uric acid levels, and neutrophil to lymphocyte ratio in acne patients

Journal of Cosmetic Dermatology, 2022
Patients suffering from moderate‐to‐severe acne are commonly treated with systemin isotretinoin; however, a great controverse about its safety had been raised. The aim of the present study is to evaluate the effects of isotretinoin on hepatic, renal, and
M. Hareedy, K. Tawfik
semanticscholar   +1 more source

The use of isotretinoin for acne – an update on optimal dosing, surveillance, and adverse effects

Expert Review of Clinical Pharmacology, 2020
Introduction Acne is a chronic, inflammatory, and immune mediated disease of pilosebaceous unit, highly prevalent in adolescents. It involves face, trunk, and back; may leave scars and affect quality of life.
E. Bagatin, C. S. Costa
semanticscholar   +1 more source

Isotretinoin for acne vulgaris – an update on adverse effects and laboratory monitoring

Journal of dermatological treatment (Print), 2021
A significant barrier to the usage of isotretinoin has been concerns regarding its adverse effect profile. The dose-dependent mucocutaneous side effects of isotretinoin are well recognized and easily managed, particularly if a lower dose is used.
H. Fallah, M. Rademaker
semanticscholar   +1 more source

Increases in uric acid and monocyte‐high‐density lipoprotein ratio as possible atherosclerotic indicators in acne patients using isotretinoin

Journal of Cosmetic Dermatology, 2021
We aimed to reveal the relationship of serum uric acid (SUA) with monocyte‐high‐density lipoprotein ratio (MHR) and other inflammatory markers in acne patients before and after isotretinoin treatment.
Nurcan Metin, Çağrı Turan
semanticscholar   +1 more source

Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters

International Journal of Dermatology, 2021
Impairment of biotin metabolism with the use of isotretinoin and the mucocutaneous side effects observed in patients using isotretinoin suggests that they are a result of decreased enzyme activity.
S. Aksac   +5 more
semanticscholar   +1 more source

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