Results 71 to 80 of about 177,330 (252)

Low‐dose digoxin improves cardiac function in patients with heart failure, preserved ejection fraction and atrial fibrillation – the RATE‐AF randomized trial

European Journal of Heart Failure, EarlyView.
Summary of the change in left ventricular systolic and diastolic parameters from baseline to 12 months in patients with permanent atrial fibrillation (AF) and a left ventricular ejection fraction (LVEF) ≥50%. P‐values indicate the significance of the adjusted mean difference of the parameters at 12 months between the beta‐blocker and digoxin arm. E/e′,
Karina V. Bunting, Asgher Champsi, Simrat K. Gill, Khalil Saadeh, A. John Camm, Mary Stanbury, Sandra Haynes, Jonathon N. Townend, Richard P. Steeds, Dipak Kotecha, on behalf of the RAte control Therapy Evaluation in Permanent Atrial Fibrillation (RATE‐AF) Trial Group   +10 more
wiley   +1 more source

Intracardiac Shunts and Role of Tissue Doppler Imaging in Diagnosis and Discrimination [PDF]

Journal of Tehran University Heart Center, 2008
Background: We sought to assess right ventricular (RV) systolic and diastolic functions via tissue Doppler imaging (TDI) in order to discriminate right-to-left (bidirectional) from left-to-right intracardiac shunts.
Mersedeh Karvandi, Mohammad Asadpour Piranfar, Arash Mohammadi Tofigh   +2 more
doaj   +2 more sources

The Preterm Heart in Childhood : Left Ventricular Structure, Geometry, and Function Assessed by Echocardiography in 6-Year-Old Survivors of Periviable Births [PDF]

, 2018
Background-Preterm birth has been associated with increased risk of cardiovascular morbidity in adult life. We evaluated whether preterm birth is associated with deviating cardiac structure and function before school start.
Broberg, Olof, Domellof, Magnus, Fellman, Vineta, Hallberg, Jenny, Halvorsen, Cecilia Pegelow, Liuba, Petru, Mohlkert, Lilly-Ann, Norman, Mikael, Rydberg, Annika, Sjoberg, Gunnar   +9 more
core   +1 more source

Consideration on Estimating Mean Pulmonary Artery Pressure Using Early Diastolic Pulmonary Regurgitation Velocity

Sonography, EarlyView.
ABSTRACT Estimation of mean pulmonary artery pressure (mPAP) using peak velocity of pulmonary regurgitation (PR) obtained via continuous‐wave Doppler echocardiography has been applied in clinical practice. However, the theoretical basis for this method and whether to include right atrial pressure (RAP) in the calculation vary across reports, with no ...
Yuichi Baba, Yuri Ochi, Daigo Hirakawa, Makoto Okawa, Toru Kubo, Naohito Yamasaki, Hiroaki Kitaoka   +6 more
wiley   +1 more source

Left ventricular flow from apex to base during systole and isovolumic relaxation in a patient with hypertrophic cardiomyopathy and midventricular obstruction [PDF]

, 2017
The occurrence of a left ventricular anterograde flow velocity (maximal: 3·9m . s−1) is demonstrated in a 32-year-old patient with hypertrophic cardioinyopathy and midveniricular obstruction, beginning at early systole and persisting throughout the ...
JENNI, R., KRAYENBÜHL, H. P., SÜTSCH, G.   +2 more
core  

Stabilisation of PRCP by deubiquitinase‐targeting chimera (DUBTAC) to replenish autophagy for ameliorating pathological cardiac hypertrophy

British Journal of Pharmacology, EarlyView.
Background and Purpose Autophagy is essential for cellular homeostasis, and its impairment contributes to cardiac hypertrophy. Modulating autophagy has shown potential in treating pathological hypertrophy. Prolylcarboxypeptidase (PRCP), a lysosomal enzyme that hydrolyzes angiotensin II to Ang1‐7, has an unclear role in cardiac autophagy and hypertrophy.
Fangchao Zhou, Jun Xia, Yingjuan Liu, Wenqi He, Hongyuan Zhang, Bernard D. Keavney, Min Zi, Binh Y. Nguyen, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Susanne S. Hille, Elizabeth J. Cartwright, Oliver J. Müller, Honglin Xu, Sam Butterworth, Xin Wang   +16 more
wiley   +1 more source

Postischemic stunned myocardium does not alter cardiac response to an elevation in contractile frequency [PDF]

, 2005
OBJECTIVE:To assess the influence of the postischemia/reperfusion stunned myocardium (PIRSM) on the inotropic and lusitropic effects of heart rate (HR).
Lopes, Antonio Carlos [UNIFESP], Murad, Neif [UNIFESP], Nogueira, Roberto J. [UNIFESP], Sant'ana Junior, Orlando [UNIFESP], Tucci, Paulo José Ferreira [UNIFESP]   +4 more
core   +3 more sources

Collagen XV preserves heart function and protects from pathological remodelling after myocardial infarction

The FEBS Journal, EarlyView.
The damage caused by myocardial infarction is exacerbated in the absence of collagen XV and leads to pathological remodelling and more severe left ventricle dysfunction (left panel) compared with the wild‐type littermates. These changes are accompanied by a wide‐ranging impact, including phenotypical (middle panel) and molecular (right panel) changes ...
Sanna‐Maria Karppinen, Miki Aho, Zoltan Szabo, Johanna Magga, Laura Vainio, Erhe Gao, Paul Janmey, Lauri Eklund, Karolina Rasi, Ilkka Miinalainen, Lynn Y. Sakai, Lasse Pakanen, Heikki Huikuri, Juhani Junttila, Risto Kerkelä, Taina Pihlajaniemi   +15 more
wiley   +1 more source

Ventricular structure, function, and mechanics at high altitude: chronic remodeling in Sherpa vs. short-term lowlander adaptation [PDF]

, 2014
Short-term, high-altitude (HA) exposure raises pulmonary artery systolic pressure (PASP) and decreases left-ventricular (LV) volumes. However, relatively little is known of the long-term cardiac consequences of prolonged exposure in Sherpa, a highly ...
Ainslie, Philip, Cotter, James D., Hughes, Michael G., Nio, Amanda, Shave, Rob, Stembridge, Mike, Stöhr, Eric J.   +6 more
core   +1 more source

Noradrenergic regulation of skeletal muscle oxygen pressures: Impact of heart failure with preserved ejection fraction and heat therapy

Experimental Physiology, EarlyView.
Abstract Attenuation of sympathetic vasoconstriction during exercise (functional sympatholysis) contributes to skeletal muscle oxygen delivery–utilization matching. However, the extent to which muscle contractions impact noradrenergic regulation of interstitial oxygen pressures (PO2is${P_{{{\mathrm{O}}_2}}}_{{\mathrm{is}}}$; the driving force for blood–
Edward T. N. Calvo, Jacob M. Pontorno, Benjamin Zeidler, Taciane M. M. Pejon, Michael D. Belbis, Scott K. Ferguson, Craig J. Goergen, Timothy P. Gavin, Bruno T. Roseguini, Igor A. Fernandes, Daniel M. Hirai   +10 more
wiley   +1 more source