Results 161 to 170 of about 5,466,595 (199)
Issue Information: (Advanced Genetics 2/07)
Advanced Genetics, Volume 7, Issue 2, June 2026.
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The crystal structure of an Asp49 phospholipase A2 from L. muta is reported, revealing a tetrameric assembly, catalytic conservation and a polarized electrostatic surface potentially linked to membrane targeting.Snake‐venom phospholipases A2 (PLA2s) are small, structurally conserved enzymes that contribute significantly to the pathophysiology of ...
Noelia Erika Neyra Chama +9 more
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This work reports the crystal structures of K214Q and K216Q variants of E. coli glucokinase, demonstrating a potential role of lysine acetylation in regulating glucokinase activity.In this study, we report the crystal structures of K214Q and K216Q variants of Escherichia coli glucokinase (ecGLK), each of which is bound to phosphate in the active‐site ...
Joseph Andrews +2 more
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A first structural model for covalent dimerization of S100 proteins
The first molecular description of a disulfide‐crosslinked S100 homodimer is revealed by the crystallographic structure of an S100A6 variant bound to the receptor for advanced glycation end‐products (RAGE). Sequence‐conservation analyses and computational modeling suggest that this covalent architecture may be adopted by other S100 proteins, thus ...
Maria Demou, Laure Yatime
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