Results 91 to 100 of about 15,183,159 (329)

At Issue

open access: yesComputing in Science & Engineering, 2008
In this installment of At Issue, two of CiSE's editorial board members describe the magazine's current and future Web presence. We start with Bill Feiereisen's discussion of science on the Web and what it could mean for CiSE ("Are We There Yet?") and end with George Thiruvathukal's discussion of the challenges therein ("If We Build It, Will They Come?")
Feireisen, Bill   +1 more
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

LIST OF RHEUMATOLOGY MEASURES IN 2015

open access: yesНаучно-практическая ревматология, 2015
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Issue Editor
doaj   +2 more sources

Vol 10 No 1 (2020)

open access: yesProfessions and Professionalism, 2020
Issue Issue
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Entire issue

open access: yesJournal of Problem Based Learning in Higher Education, 2023
Full issue
doaj   +1 more source

In This Issue

open access: yesJournal of MultiDisciplinary Evaluation, 2005
This is a particularly exciting issue, for several reasons. First, we have an important paper by Tom Cook (describing what is special about the role of experiments, etc.) which goes a long way towards defining a compromise on the ‘causal wars’ issues, as I try to spell out in a few comments, and Jane Davidson discusses in her editorial.
openaire   +6 more sources

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