Results 51 to 60 of about 14,516,654 (291)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Volume 10, Issue 2: Full Issue [PDF]
, 2014 Full issue of the March 2014 issue of Manuscripts. Includes work by: Lucy Kaufman, Thomas J. Luck, Mary M. Schortemeier, Verse Forms Class, Jeanne Gass, Jack DeVine, Mildred Reimer, Donald Rider, Donald Morgan, Joe Howitt, Elizabeth Hyatt, Arline Hyde ...
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
ON THE OCCASION OF THE 70TH BIRTH ANNIVERSARY OF ACADEMICIAN VADIM IVANOVICH MAZUROV
Научно-практическая ревматология, 2015 .
Issue Editor
doaj +2 more sources
Themed issue: Optofluidics [PDF]
, 2012 The term optofluidics defines a growing research area that integrates optics and microfluidics in ways that enable unique strengths and advantages for a broad range of applications.
Liu, Ai-Qun, Yang, Changhuei
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
International Psychogeriatrics, 2003 Any medical decision generates consequences for the patient and for society. Medical practice should, therefore, be performed under the guidance of the following ethical principles: beneficence, nonmaleficence, autonomy, justice, integrity, dignity, and vulnerability.
José L, Molinuevo, Rafael, Blesa
openaire +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Volume 4, Issue 2: Full Issue [PDF]
, 2014 Full issue of the January 1937 issue of Manuscripts. Includes work by Wayne Hill, Margaret Pierson, Elizabeth Messick, Margaret Kendall, Mary Burrin, Grace Ferguson, Betty Richart, Charles Aufderheide, Dorothy Steinmeier, Mars B.
core +1 more source