Results 61 to 70 of about 56,280 (306)

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Career aspirations among specialty residents in France: a cross-sectional gender-based comparison

BMC Medical Education, 2021
Background Most studies evaluating career aspirations among gender are performed in Anglo-Saxon countries. Two recent French studies looked at the career choice of residents in obstetrics & gynecology.
A. Cathelain, M. Jourdain, C. Cordonnier, S. Catteau-Jonard, D. Sebbane, M. C. Copin, L. Berlingo, C. Rubod, C. Garabedian   +8 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

What it means to succeed: personal conceptions of career success held by male and female managers at different ages [PDF]

, 1996
The aim of this research is to investigate how managers define career success for themselves. It seeks to discover what differences there are in the way that women and men, and older and younger managers, see their own career success.
Sturges, J., Sturges, Jane
core  

Modeling the student choice–Perception–Realization lifecycle: A methodological framework with synthetic data illustration

Social Sciences and Humanities Open
A student’s choice of higher education institution has enduring consequences extending beyond academics, affecting career trajectories and economic outcomes.
Animesh Karn, Pallavi Kumari, Arohi Anand   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Is the boundaryless career applicable to all? An investigation of black knowledge intensive workers in the UK [PDF]

, 2013
This thesis is submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This study explores protean and boundaryless career attitudes in a sample of black British knowledge intensive workers. Changes in the organisational climate
Mansah-Owusu, Grace
core  

Conceptual model of professional orientation of the population in regard to the profession of an “investigator”

Law and Safety, 2018
The main approaches to constructing a conceptual model of professional orientation of the population regarding the choice of an investigator’s profession have been provided.
N. E. Miloradova
doaj   +1 more source

Immersion in the Profession: Experience of Career Guidance Work at Medical University

Высшее образование в России, 2020
Higher medical education places high demands to the quality of applicants’ knowledge, assumes the awareness of their choice of future profession. As practice shows, often this choice is made by high school students at the level of momentary desires ...
P. V. Tkachenko, S. V. Cherney, E. А. Kovaleva   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source