Results 61 to 70 of about 171,751 (265)

Convergence of functional areas in information operations

South African Journal of Information Management, 2015
Background: Contemporary technology and its rapid rise to a ubiquitous nature are affecting the way in which technology is used. This holds implications for military information operations and information warfare concepts as the previously separate ...
Brett van Niekerk
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The misnomer of ‘service delivery protests’ in South Africa: Discourse, governance and institutional accountability

Journal of Local Government Research and Innovation
Background: In South Africa, the term ‘service delivery’ has become ubiquitous in public discourse, encompassing a wide array of issues from water outages to damaged roads.
Betty C. Mubangizi
doaj   +1 more source

Knowledge management as a strategic tool for human resource management at higher education institutions

South African Journal of Information Management, 2018
Background: Higher education institutions (HEIs) the world over are beginning to recognise the importance of knowledge management; however, such institutions are still in their formative stages of addressing, evaluating and implementing the benefits of ...
Loganathan N. Govender, Rubeshan Perumal, Sadhasivan Perumal   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

COVID-19 and Digital Transformation in Higher Education Institutions: Towards Inclusive and Equitable Access to Quality Education

Education Sciences
While the impact of the COVID-19 pandemic has affected both developing and developed countries, students from disadvantaged groups have suffered significantly.
Molefi Matsieli, Stephen Mutula
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Technological Innovation and Commercial Banks' Financial Performance: A Mediation Analysis of Risk Management Practices

SEISENSE Business Review
The purpose of the study is to investigate the association between technological innovations and the financial performance of commercial banks using risk management practices as a mediator.
Mahadih Kyambade, Rehema Kagere, Afulah Namatovu, Abdul Male Ssentumbwe, Monica Tushabe, Sheilla Oyella   +5 more
doaj   +1 more source

Decoupling paradigm of push-pull theory of oscillation in the FMCG industry

South African Journal of Business Management, 2016
The amplification of demand order variability germinates from distorted demand information upstream while sometimes reacting to demand-driven inventory positioning influenced by the custodians of downstream information. This study uses factor analysis to
T.P. Mbhele
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source