Results 91 to 100 of about 3,604,006 (311)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

IT Management

open access: yes, 2014
Will there ever be a day IT personnel and Business persons get along? It is almost impossible to talk about information technology without discussion about IT management.
Reppe, Kameron
core   +1 more source

Shadow IT Management Concept for Public Sector

open access: yes, 2019
Part 2: Technical Architecture and Applications for EISInternational audienceShadow IT represents a software, hardware, or any other solution used by employees within organizations that has not received any prior formal approval from the IT department to
Lada Šedivcová   +3 more
core   +1 more source

Select the Appropriate Methodology for Developing Information System, Using Decision Techniques (Case Study: Billing of public Warehouses Company and West Tehran Customs) [PDF]

open access: yesمطالعات مدیریت کسب و کار هوشمند, 2014
Along with advances in technology and communications, global markets and competition between Companies are intensifying. Literature review of Methodologies to build Information Systems suggests that by development of Methodologies, we are seeing the ...
Ali Mehrabi, Foad Fasihi, Ramin Assari
doaj  

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

ITIL tools in IT management

open access: yes, 2020
Maģistra darbā tiek apskatīti nosacījumi labas IT pārvaldības nodrošināšanai, vadoties pēc ITIL pamatprincipiem. Darbā tiek praktiski analizēti IT pārvaldības nodrošināšanas paņēmieni trīs reālos uzņēmumos.
Ozoliņa, Diāna
core  

Managing human resourses in project IT management [PDF]

open access: yes, 2009
About managing human resourses in project IT ...
Krajcik, Ph. D.
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Tools for monitoring software quality in information systems development and maintenance: five key challenges and a design proposal

open access: yesInternational Journal of Information Systems and Project Management
As software grows in size and complexity, organizations increasingly apply tools to automatically assess software quality of information systems during development and maintenance.
Rolf-Helge Pfeiffer, Jon Aaen
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

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