Results 81 to 90 of about 3,604,006 (311)

Multi-center disease-specific management system: toward standardized and harmonized clinical pathways in integrated care networks

Frontiers in Public Health
IntroductionWest China Hospital of Sichuan University leads the largest regional medical alliance in Western China, coordinating complex referrals and continuity of care.
Xiang Liu, Rui Zhang, Tao Zheng, Ran Liu, Siyuan Zhang, Hongsen Zhao, Jing Dong, Siqi Chen, Jia Xu, Rui Shi, Rui Shi, Rui Shi   +11 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Advanced IT Management (Supp)

, 2014
Exam paper for second semester: Advanced IT Management ...
University of Johannesburg
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

['EXPERIMENTAL INVESTIGATION OF DURABILITY AND STRENGTH OF SANDSTONE AND SHALE OF UNITED MINERAL COAL COMPANY SOR-RANGE, BALOCHISTAN']

Journal of Mountain Area Research, 2022
Tufail Ahmed, Syed Hafeez Ur Rehman, Fahim Ahmed Ibupoto, Asif Abbas, Sami Ullah, Abbas Hussain, Shehzad Usman   +6 more
doaj   +1 more source

Nonbinary Voices for Digital Assistants—An Investigation of User Perceptions and Gender Stereotypes

Robotics
Due to the wide adoption of digital voice assistants (DVAs), interactions with technology have also changed our perceptions, highlighting and reinforcing (mostly) negative gender stereotypes.
Sonja Theresa Längle, Stephan Schlögl, Annina Ecker, Willemijn S. M. T. van Kooten, Teresa Spieß   +4 more
doaj   +1 more source

Factors influencing demand forecasting and planning in the South African apparel industry : a case study [PDF]

The Retail and Marketing Review, 2020
The apparel industry has become highly competitive and complex as consumers’ demands vary, thus pressuring organisations in this sector to invest in better demand forecasting and planning tools.
F Katemauswa, M Naude
doaj  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Der Einsatz von grünem Tee und anderen Polyphenolen in der Medizin ‒ eine Big-Data-Analyse der medizinischen Fachliteratur

, 2021
Um Anwendungsmöglichkeiten, Behandlungsgebiete und Wirkweisen der Inhaltsstoffe von grünem Tee zu erforschen, ist es erforderlich, zunächst einen Überblick über das existierende Fachwissen und bisherige Forschungsansätze zu erlangen.
Braka, Daniel, Gomes, Daniel, Pachocki, Christian, Walter, Annika, Burchard, Patrick, Demary, Marius, Kaiser, Julian, Dragieva, Martina, Urban, Philipp, FOM Hochschule für Oekonomie & Management, Institut für IT-Management & Digitalisierung (ifid), Krüger, Robert, Eis, Luke, Schade, Johannes Christian, Hacker, Milan, Marks, Alexander, Buchkremer, Rüdiger, Yesilyurt, Erdal, Winter, Viviane, Farid, Abdul Tanwir, Cyron, Stanley, Luu, Simone, Bähren, Tobias, Pongratz, Michael, Maasjosthusmann, Robin   +23 more
core  

Measurement of IT Management Sophistication in Small Firms [PDF]

, 2020
This study developed an instrument to measure IT management sophistication in small firms. Multiple-case studies were used to explore the concept of IT management sophistication in small firms and provide a pool of indicators representing IT management ...
Cragg, Paul, Mills, Annette, Suraweera, Theekshana   +2 more
core