Results 61 to 70 of about 3,604,006 (311)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
EXPERIENCE MANAGEMENT FOR IT MANAGEMENT SUPPORT
, 2012 This thesis focuses on the identification of experience required for solving IT (Information Technology) problems in small to medium sized enterprises.
Bozdogan, Can
core
, 2014 Exam paper for first semester IT Management ...
Bello, O., Dr., Toko, G., Mr.
core +2 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Trust-based energy-efficient routing protocol for Internet of things–based sensor networks
International Journal of Distributed Sensor Networks, 2020 Internet of things grew swiftly and many services, software, sensors-embedded electronic devices and related protocols were developed and still in progress with full swing.
Muhammad Ilyas +6 more
doaj +1 more source
The Journal for Transdisciplinary Research in Southern Africa, 2020 This article explores women’s entrepreneurship research conducted in Zimbabwe. For this purpose, a literature review approach was adopted where all journal articles published between 1990 and 2018 that addressed the issues of women entrepreneurship in ...
Evelyn Derera +3 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
, 2009 Business-driven IT management (BDIM) aims at ensuring successful alignment of business and IT through thorough understanding of the impact of IT on business results, and vice versa.
Bartolini, Claudio
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source