Results 31 to 40 of about 355,493 (267)

Flooding, Food Security and the Sustainable Development Goals in Nigeria: An Assemblage and Systems Thinking Approach

open access: yesSocial Sciences, 2022
Food is connected to sustainable development goals in numerous ways, as food security is key to achieving sustainable development. The world is currently not on track to achieve the set sustainable development goals (SDGs).
Adaku Jane Echendu
doaj   +1 more source

Paths for Improving Public Service Capability Regarding Industrial Internet Security

open access: yes中国工程科学, 2021
Industrial Internet security public service ensures the healthy development of the industrial Internet, as it is an important approach for outputting the industrial Internet security capability.
Zhou Hao   +4 more
doaj   +1 more source

Monitoring tools of regional economic security [PDF]

open access: yesE3S Web of Conferences, 2019
Ensuring the economic security of the region is one of the key tasks of the management of the federal entity. By ensuring economic security, the priorities of the management of the region are determined, so that the system of economic security should be ...
Husainova E.A.   +4 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Supporting Survivor‐Centered Care Through Digital Health Integration

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Survivors of childhood cancer face barriers to receiving guideline‐based, long‐term follow‐up care. Two digital tools, Passport for Care (PFC) and Cancer SurvivorLink (SurvivorLink), address complementary gaps by enabling tailored survivorship care plan (SCP) generation, updating, storage, and sharing.
Jordan G. Marchak   +15 more
wiley   +1 more source

INNOVATIVE SECURITY: THE BASIC CONCEPTS, ESSENCE

open access: yesНаука и техника, 2016
Some theoretical and methodological aspects of a role and value of innovative security in system of national security of the state are considered. The basic concepts of innovative security, essence of innovative security in formation of innovative ...
V. A. Sakovich, G. M. Brovka
doaj   +1 more source

Urban ecological security assessment and path regulation for ecological protection - A case study of Shenzhen, China

open access: yesEcological Indicators, 2022
The rapid development of urbanization has triggered the contradiction between population, resources and environment. As a result, urban ecological security has attracted more and more attention, and has gradually become the key to restricting the ...
Shu Tian   +11 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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