Results 51 to 60 of about 355,493 (267)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Ensuring Regional Security in the Context of Economic Aspects of Sustainable Development

E3S Web of Conferences, 2018
Sustainable development is one of the priorities of the world development. It combines the need for simultaneous harmonious development of society in ecological, economic and social areas.
Kazantseva Elena, Chistyakova Galina
doaj   +1 more source

Forming connections between security sector reform and sustainable development: The potential of the human security paradigm [PDF]

Journal of Regional Security
Many interlinkages already exist between security and development, despite the fact they traditionally maintained separate bodies of literature and compartmentalized presence in policymaking.
Dursun-Özkanca Oya, Glušac Luka
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Ensuring National Security under Martial Law Conditions: Legal Regulation, Threats, Cooperation and Directions for Improvement

Khazanah Hukum
The purpose of the article is to reveal the legal regulation of ensuring national security in the conditions of martial law (threats, cooperation and directions for improvement).
Andrii Nosach, Sergii Melnyk, Anatolii Rusetskyi, Yuliia Pinchuk, Volodymyr Piadyshev   +4 more
doaj   +1 more source

SECURITY IN SUSTAINABLE DEVELOPMENT: COMPARING UNITED NATIONS 2030 AGENDA FOR SUSTAINABLE DEVELOPMENT WITH MILLENNIUM DECLARATION

Mehmet Akif Ersoy Üniversitesi İktisadi ve İdari Bilimler Fakültesi Dergisi, 2017
This study aims to compare United Nations 2030 Agenda for Sustainable Development with Millennium Declaration in terms of their security conceptualizations to explore changes in security thinking and policy components (goals, targets, principles ...
Ahmet Barbak
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Financial Organization Information Security System Development using Modeling, IT assets and Accounts Classification Processes

Безопасность информационных технологий, 2013
This article deals with processes of modeling, IT assets and account classification. Key principles of these processes configuration are pointed up. Also a model of Russian Federation banking system organization is developed.
Anton Sergeevich Zaytsev
doaj  

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source