Results 151 to 160 of about 12,596,900 (345)
International Journal of Research in E-Learning, 2015 The article describes some preliminary results of the implementation of Work- Package 4 (WP4) “Selection and testing new IT tools” in the framework of the international research network (IRNet) and researchers from partner institutions from Poland ...
Eugenia Smyrnova-Trybulska +13 more
doaj
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
"Learn to p-hack like the pros!"
, 2019 The replication crisis has hit several scientific fields. The most systematic investigation has been done in psychology, which revealed replication rates less than 40% (Open Science Collaboration, 2015). However, the same problem has been well documented
Schönbrodt, F.
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The risk in IT projects – statistical evaluation tools
Contemporary Economy, 2012 The purpose of this article is to present the possibility of using statistical tools to assess the magnitude of the threat of projects. The text presents the author’s interpretation of the phenomenon of the risk inherent in the process of implementing IT
Jacek Winiarski
doaj
TRENDS IN THE DEVELOPMENT OF SCIENCE AND EDUCATION, 2020 ZH.V. Idrisova +2 more
openaire +1 more source
A literature review of the use of Web 2.0 tools in Higher Education
, 2010 This review focuses on the use of Web 2.0 tools in Higher Education. It provides a synthesis of the research literature in the field and a series of illustrative examples of how these tools are being used in learning and teaching.
Alevizou, Panagiota, Conole, Grainne
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source