Results 31 to 40 of about 332,360 (260)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

El sueño de Venecia de Ángel Crespo

Cuadernos AISPI
Se trata de un diario, en gran parte inédito, que aborda la estancia del poeta, traductor y ensayista Ángel Crespo, en 1982, como profesor invitado en la Universidad de Venecia, donde estuvo acompañado por su esposa, la profesora Pilar Gómez Bedate ...
Fernando Valls
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Cronologia, Bibliografia critica e Nota al testo del Deserto della Libia di Mario Tobino

, 2011
Cronologia della vita di Mario Tobino e Bibliografia della critica del romanzo Il deserto della Libia, pubblicato da Einaudi nel 1952 e ora ristampato, a cura di Paola Italia e Giulia Fanfani, con l'inedito Libro della Libia, una prima redazione di ...
ITALIA, PAOLA MARIA CARMELA
core   +1 more source

Parità di genere e indipendenza dell’avvocatura tra prospettive storiche e contemporanee

Italian Review of Legal History
Si propone una riflessione sulla parità di genere in connessione con il principio di indipendenza della professione forense attraverso un’analisi storica tra età liberale, fascismo e periodo repubblicano sino ai giorni nostri. Se, da un lato, infatti, l’
Raffaella Bianchi Riva
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Demolingüística del español en Italia, con un anexo sobre Malta, San Marino y Ciudad del Vaticano

Cuadernos AISPI
Milin Bonomi, Maria Vittoria Calvi, Marcella Uberti-Bona (eds.), Demolingüística del español en Italia, con un anexo sobre Malta, San Marino y Ciudad del Vaticano, Madrid, Instituto Cervantes, Universidad de Heidelberg, Universidad de Zurich, 2024, 246 ...
Sonia Bailini
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Nuevas aproximaciones a la historia urbana de Italia: el Renacimiento temprano

Hispania, 1998
La interpretación de la historia de la Baja Edad Media y la temprana Edad Moderna de Italia ha estado desde el siglo pasado fuertemente influida por la dicotomía norte-sur y los modelos centro-periferia. Este artículo desmonta los argumentos del dualismo
S. R. Epstein
doaj   +1 more source