Results 41 to 50 of about 250,427 (303)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Nuevas aproximaciones a la historia urbana de Italia: el Renacimiento temprano

Hispania, 1998
La interpretación de la historia de la Baja Edad Media y la temprana Edad Moderna de Italia ha estado desde el siglo pasado fuertemente influida por la dicotomía norte-sur y los modelos centro-periferia. Este artículo desmonta los argumentos del dualismo
S. R. Epstein
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Derecho y práctica legal en las comunas urbanas italianas del siglo XII: el caso de pisa

Hispania, 1997
Pisa no fue una ciudad típica en la Italia del siglo XII; grande y comercialmente próspera, con instituciones urbanas precoces, destaca, sobre todo, por su adopción del Derecho Romano con un grado de compromiso mayor que cualquier otra entidad política a
Chris Wickham
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Italia

Ciudad y Territorio Estudios Territoriales
di Giovanni Antonio Magini; data in luce da Fabio suo ...
  +6 more sources

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

NOTA AL TESTO a SAVINIO, SCRITTI DISPERSI

, 2004
Gli "Scritti dispersi" di Alberto Savinio, pubblicati in varie sedi dal 1943 al 1952 vengono qui raccolti nel terzo volume delle Opere di Alberto Savinio pubblicate nella collana La Nave Argo, dirette da Alessandro Tinterri e Paola Italia.
ITALIA, PAOLA MARIA CARMELA
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

El impacto de los derechos europeos (CEDH y derecho de la Unión) en la justicia constitucional italiana

Revista del Posgrado en Derecho de la UNAM, 2015
El objetivo de este artículo es presentar las principales tendencias de la jurisprudencia del Tribunal Constitucional italiano en materia de derecho de la Unión Europea (UE) y del Convenio Europeo de Derechos Humanos (CEDH). El artículo se divide en tres
Giuseppe Martinico
doaj   +1 more source