Results 71 to 80 of about 669,045 (267)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Il “Sogno” di un collezionista del Seicento napoletano. Maurizio Di Gregorio tra riscrittura e plagio [PDF]

open access: yesParole Rubate, 2011
Sogno and Rosario delle stampe de tutti i poeti e poetesse antichi e moderni di numero 500 by the Dominican friar and idle academic Maurizio Di Gregorio were published in Naples in 1614.
Daniela Caracciolo
doaj  

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Italian Alterdisciplinarity

open access: yesJOMEC Journal, 2015
The aim of this paper is to analyse the consequences, problems and possible opportunities derived from the absence of Cultural Studies as a specific and autonomous\ud ‘discipline’ in the Italian University, despite its wide diffusion across various academic subjects since the 1970s.
openaire   +2 more sources

Processing Dante’s Commedia: From Sanguineti’s Edition to Digital Tools

open access: yesRIDE, 2015
The Commedia project aims to investigate the manuscript transmission of the poem, using Sanguineti's previous edition and checking the validity of his stemma with computer methods.
Elena Spadini
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

‘Women and Work’: a Cross-Linguistic Corpus-Assisted Discourse Study in German and in Italian

open access: yesCritical Approaches to Discourse Analysis across Disciplines, 2018
In recent years, interest towards CADS has significantly grown but cross-linguistic analysis still represents a small niche in this research field, as emphasized in Partington et al. 2013.
Chiara Nardone
doaj  

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

S + V + O : Ordres marqués et non marqués en italien

open access: yesDiscours, 2017
The article aims to discuss the notions of marked and unmarked orders, as they are used in the works describing the norms and properties of languages, particularly their grammars.
Sandra Augendre
doaj   +1 more source

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