Results 51 to 60 of about 9,144 (262)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
“Imperfetto perfettismo”: le riforme costituzionali nell’Italia del secondo dopoguerra. Intervista a Giuseppe Carlo Marino [PDF]
Diacronie. Studi di Storia Contemporanea, 2016 In the interview sent to Diacronie. Studi di Storia contemporanea on 18th August 2016, the historian Giuseppe Carlo Marino recalls the basic aspects of the italian political contemporary history by focusing on the institutional dynamics that have to do ...
Giuseppe Carlo Marino +1 more
doaj
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Acta Scientiarum. Education, 2014 Current paper is the partial result of a research, funded by CNPq, on the History of the Italian Ethnic Community Schools inBrazil (1875-1945). Investigating and mapping school organizations established by Italian immigrants in the state ofRio Grande ...
Terciane Ângela Luchese +2 more
doaj +1 more source
Implicit and explicit “European clauses” in the Italian Constitution
, 2022 The contribution analyzes the links between the Italian Constitution and the process of European integration, which are generally outlined by what are called “European clauses”: the constitutional provisions – contained in the original text of the ...
Lupo, Nicola
core
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Calamandrei e Bobbio: cultura, diritto e politica come percorsi di giustizia [PDF]
Democrazia e Diritti SocialiTis article takes into account the intellectual collaboration of Piero Calamandrei and Norberto Bobbio during the period from the Second World War to 1956. Calamandrei’s and Bobbio’s approaches to culture, law and politics are comparatively investigated,
Marcello Gisondi
doaj
Criteria and methods for the assessment of animal welfare - Presentation
Italian Journal of Animal Science, 2010 With the constitution of the Commission “Criteria and methods for the assessment of animal welfare,” the Scientific Association of Animal Production (ASPA) intended to underscore the importance of a subject matter that qualifies animal ...
Pierlorenzo Secchiari
doaj +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source