Results 171 to 180 of about 2,583,059 (299)

From Genome Inspection to Precision Agrochemicals: A Structure-Based Antivirulence Roadmap for Sustainable Crop Protection against <i>Xylella fastidiosa</i>. [PDF]

J Agric Food Chem
Caliandro R, Astolfi A, Amoia SS, Belviso BD, Mangini V, Rodrigues De Souza Neto R, Sciancalepore AG, Sabatini S, Giampetruzzi A, Barreca ML, Caliandro R.   +10 more
europepmc   +1 more source

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

British Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić, Elvira Meni Maria Gkrinia, Patrick Eustaquio, Andrea Katrin Faour, Dinko Vitezić   +4 more
wiley   +1 more source

Evolution and determinants of firm-level systemic risk in local production networks. [PDF]

PNAS Nexus
Mancini A, Lengyel B, Di Clemente R, Cimini G.   +3 more
europepmc   +1 more source

Current evidence and insights on single vs. double dose of basiliximab in adult solid organ transplant recipients: A systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this systematic review was to assess all available clinical data regarding the use of a single dose of basiliximab in solid organ transplantation compared to the standard double dosage, with particular interest in efficacy, safety and cost‐savings.
Alessio Provenzani, Braidon A. Lape, Anneliese M. Harp, Victoria Weisbrod, Lavinia Piazza   +4 more
wiley   +1 more source

Celebrating Rodolfo Margaria and applied physiology in Milan. [PDF]

Exp Physiol
Minetti AE, Pavei G, Bailey DM.
europepmc   +1 more source

Correction to 'The Genetics of Portal Hypertension: Recent Developments and the Road Ahead'. [PDF]

Liver Int
europepmc   +1 more source

From environmental burden to resource potential: environmental impact evaluation and Critical Raw Materials recovery from abandoned gold mining waste in the Western Alps (NW Italy). [PDF]

Environ Sci Pollut Res Int
Zaniboni L, Cavallo A, De Luca DA, Lasagna M, Padoan E, Martin M, Dino GA.   +6 more
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Sustainable entrepreneurship between ecological distinction and local context. [PDF]

Front Sociol
Azzolina L, Mazzenzana S.
europepmc   +1 more source

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source