Results 151 to 160 of about 639,783 (293)

Correction: Chronic administration of Metformin exerts cytostatic and cytotoxic effects via the PP2A-GSK3β-MCL-1 pathway by inhibiting the tmCLIC1 membrane protein in glioblastoma-initiating cells. [PDF]

open access: yesJ Exp Clin Cancer Res
Cianci F   +24 more
europepmc   +1 more source

Understanding the Adoption of Artificial Intelligence in Local Government Decision‐Making: The Influence of Institutional Pressures and Managerial Perceptions

open access: yesPublic Administration, EarlyView.
ABSTRACT Artificial intelligence (AI) systems are increasingly being integrated into public sector decision‐making processes, with public managers relying on them to enhance their capabilities. As AI adoption becomes more widespread, discussions about its advantages and drawbacks intensify, alongside growing external expectations and pressures. However,
A. Paula Rodriguez Müller   +2 more
wiley   +1 more source

Humanism at the Council of Constance. Diego de Anaya, Classical Manuscripts and Education in Salamanca

open access: yesRenaissance Studies, EarlyView.
Abstract Due to their prolonged and multicultural nature, councils functioned historically as hubs for the exchange of ideas, discourse, diplomacy and rhetoric, reflecting broader cultural trends. In the Middle Ages, no international forums were comparable to ecumenical councils, where diverse and influential groups from various regions convened to ...
Federico Tavelli
wiley   +1 more source

A combination of modified Kuhnt–Szymanowski and Celsus–Hotz techniques for correction of entropion and overlong lower eyelids in dogs (40 eyes)

open access: yesVeterinary Ophthalmology, Volume 28, Issue 2, Page 114-123, March 2025.
Abstract Purpose To describe a surgical approach to correct entropion and overlong lower eyelids in dogs by combining the Celsus–Hotz with the modified Kuhnt–Szymanowski technique. Methods Medical records of patients undergoing the described surgical procedure were reviewed.
Hanna Walter   +3 more
wiley   +1 more source

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

open access: yesExperimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti   +6 more
wiley   +1 more source

Changes in motor unit conduction velocity after unilateral lower‐limb suspension and active recovery are correlated with muscle ion channel gene expression

open access: yesExperimental Physiology, EarlyView.
Abstract The effects of muscle disuse on the propagation of action potentials along motor unit (MU) muscle fibres, a key process for effective muscle activation and force generation, remain poorly understood. The aim of this study was to investigate changes in action potential propagation and to identify biological factors influencing these changes ...
Giacomo Valli   +12 more
wiley   +1 more source

Impaired nitric oxide‐dependent endothelial function in young male individuals with obesity before the onset of symptoms and complications

open access: yesExperimental Physiology, EarlyView.
Abstract Endothelial dysfunction drives obesity‐related complications. Doppler ultrasound measurement of blood flow during 1‐min passive leg movements (PLM) is a valuable non‐invasive tool for assessing endothelial function and nitric oxide (NO)‐mediated vasodilation.
Lucrezia Zuccarelli   +13 more
wiley   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti   +2 more
wiley   +1 more source

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