Results 51 to 60 of about 4,249,042 (310)

ITALIE

open access: yesRESAP, 1910
R. M. Italie. In: La revue pédagogique, tome 56, Janvier-Juin 1910. p. 387.
openaire   +3 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Access to the Internet and Regional Structures: The Case of Italy [PDF]

open access: yes, 2016
I study the effects of Internet access on regional structures and provide some insights into the complex question of the role of technology in regional development.
Gualerzi, Davide
core   +1 more source

Axial torsion waves in metric-affine gravity

open access: yes, 2017
We construct new explicit vacuum solutions of quadratic metric-affine gravity. The approach of metric-affine gravity in using an independent affine connection produces a theory with 10+64 unknowns, which implies admitting torsion and possible ...
Barakovic, Elvis, Pasic, Vedad
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Climate Events and Insurance Demand - The effect of potentially catastrophic events on insurance demand in Italy [PDF]

open access: yes, 2014
Climate extreme events are constantly increasing. What is the effect of these potentially catastrophic events on insurance demand in Italy, with particular reference to the economic activities?
Chieppa, Alessandro   +2 more
core   +1 more source

On a filtered multiplicative basis of group algebras

open access: yes, 2000
Let $K$ be a field of characteristic $p$ and $G$ a nonabelian metacyclic finite $p$-group. We give an explicit list of all metacyclic $p$-groups $G$, such that the group algebra $KG$ over a field of characteristic $p$ has a filtered multiplicative $K ...
Bovdi, Victor   +1 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy