Results 61 to 70 of about 4,217,420 (261)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

"This shame, it is everywhere": Cross-generational menstruation experiences among women living in Florence, Italy

open access: yesHealth Behavior Research
Menstruation is a worldwide biological phenomenon that can have differing impacts based on what women were taught by their family members and friends. The purpose of this investigation was to understand menstruation experiences and communication, from ...
Anna G. Trieloff   +7 more
doaj   +1 more source

Parents' insights after pediatric hospitalization due to rotavirus gastroenteritis in Italy

open access: yesHuman Vaccines & Immunotherapeutics, 2017
Most of the severe cases of acute gastroenteritis in infants and children under 5 globally are caused by rotavirus infection. There are nearly 15,000 rotavirus gastroenteritis (RVGE) hospitalizations in Italy each year, which could be reduced by ...
Federico Marchetti   +4 more
doaj   +1 more source

On International Scientific and Educational Cooperation with Italy

open access: yesInformaciâ i Innovacii, 2019
This article presents the results of the analysis of the current state of international scientific and educational cooperation with Italy through the Ministry of Science and Higher Education of the Russian Federation.
A. Ridiger, O. Guzenyuk
doaj   +1 more source

Single-spin asymmetries: the Trento conventions [PDF]

open access: yes, 2004
During the workshop "Transversity: New Developments in Nucleon Spin Structure" (ECT*, Trento, Italy, 14-18 June 2004), a series of recommendations was put forward by the participants concerning definitions and notations for describing effects of ...
Bacchetta, Alessandro   +3 more
core   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Organic farming in Italy [PDF]

open access: yes, 2002
History and situation of OF in Italy: The recent growth of organic sector in Italy can be considered a success story that deserves to be properly known and analysed.
Pignataro, Filippo   +1 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Antik Yunan’dan Viyana Kongresi’ne Avrupa Diplomasi Tarihinde Elçiler

open access: yesUniversal Journal of History and Culture
Diplomasi günümüze kadar birçok dönüşüm geçirmiş ve sürekli çeşitlenerek gelişim göstermiştir. Başlangıçta sadece ad hoc (geçici) diplomasi uygulamaları kullanılırken, zaman içerisinde başka diplomasi türleri ortaya çıkmış ve 15.
Mehlika Özlem Ultan Sönmez
doaj   +1 more source

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