Results 171 to 180 of about 2,204 (211)
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The physiology of itch

Parasitology Today, 1986
The perception of itch is associated with many parasites and their vectors, especially following penetration of the skin by the parasites themselves, as in cercarial dermatitis of schistosome infections, or penetration of arthropod mouthparts during blood feeding.
openaire   +2 more sources

Itching for relief

Nature Neuroscience, 2013
Little is known about the molecular and cellular mechanisms underlying acute and chronic itch. A new technique for silencing peripheral itch neurons defines two independent itch circuits that transmit signals to the CNS.
Sarah, Wilson, Diana, Bautista
openaire   +2 more sources

Pathophysiology of itching

The Lancet, 1996
Itching is the predominant symptom of skin disease but it is ill-understood and a challenge for future research. Even the major nerve pathways for itch, and its relationship to pain are debatable. In inflamed skin, histamine plays a major role and its mode of release from mast cells in, for example, chronic urticaria is now better appreciated ...
M W, Greaves, P D, Wall
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When an itch is not just an itch

Annals of Allergy, Asthma & Immunology, 2023
R. Christina Smith   +2 more
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The neurobiology of itch

Nature Reviews Neuroscience, 2006
The neurobiology of itch, which is formally known as pruritus, and its interaction with pain have been illustrated by the complexity of specific mediators, itch-related neuronal pathways and the central processing of itch. Scratch-induced pain can abolish itch, and analgesic opioids can generate itch, which indicates an antagonistic interaction ...
Akihiko, Ikoma   +4 more
openaire   +2 more sources

Itch and Eczema

2012
Eczema/dermatitis belongs to the most pruritic of skin diseases. Pruritogenic mediators in the skin are still mostly unknown. Recent studies, however, have shown that the histamine 4 receptor plays an important role in itch pathophysiology; tryptase and IL-31 are also involved in atopic eczema itch.
Ulf, Darsow   +4 more
openaire   +2 more sources

Antihistamines and Itch

2015
Histamine is one of the best-characterized pruritogens in humans. It is known to play a role in pruritus associated with urticaria as well as ocular and nasal allergic reactions. Histamine mediates its effect via four receptors. Antihistamines that block the activation of the histamine H₁receptor, H₁R, have been shown to be effective therapeutics for ...
Robin L, Thurmond   +3 more
openaire   +2 more sources

A basophil-neuronal axis promotes itch

Cell, 2021
Mark Miller   +2 more
exaly  

Itching in a Teenager

Clinical Pediatrics, 2011
Chang, Alicia K.   +2 more
openaire   +5 more sources

S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis

Cell, 2023
Juan Manuel Leyva Castillo   +2 more
exaly  

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