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Neurologic insults as varied as inflammation, stroke, and fibromyalgia elicit neuropathic pain and itch. Noxious sensation results when aberrantly increased afferent signaling reaches percept-forming cortical neurons and can occur due to increased sensory signaling, decreased inhibitory signaling, or a combination of both processes.
James Meixiong+2 more
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Topical medicines in the treatment of allergodermathosis in children
The article tells about the basic principles of local treatment of allergodermathosis in children and medicines used in the acute and remission stages; there is data on the efficacy and safety of the medicines.
I. V. Khamaganova, D. F. Kashevarov
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The description of itch (formally known as pruritus) as an "unpleasant sensation that elicits the desire or reflex to scratch" (Ikoma et al., 2006) is immediately familiar. Research in the field of pruritoception has added to our understanding of this area of sensory neurobiology as it pertains to both normal and pathological conditions. In particular,
Kush N. Patel+2 more
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Efficiency of fenticonazole for the treatment of vaginal candidiasis [PDF]
Introduction. Uncomplicated vulvovaginal candidiasis appears in 75% women of reproductive age. The most frequent causes are Candida albicans (85-95%) or C. glabrata, and infrequently C. krusei, C. tropicalis, C. parapsilosis, C. pseudotropicalis, etc.
Živaljević Biljana+8 more
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Anti-Itching and Anti-Inflammatory Effects of Kushenol F via the Inhibition of TSLP Production
Atopic dermatitis (AD) is a chronic inflammatory skin disease that results from eczema, itching, disrupted barrier function and aberrant cutaneous immune responses.
Seongyea Jo+8 more
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Can the Pessary Use Modify the Vaginal Microbiological Flora? A Cross-sectional Study [PDF]
Introduction Vaginal pessary is used as a conservative treatment for pelvic organ prolapse (POP). Some studies have shown that common complaints of its use may include vaginal discomfort and increased vaginal discharge.
Suelene Costa de Albuquerque Coelho+5 more
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It is well known that objectionable fibres emerge from the surface of the yarn due to the centrifugal force of the spinning device. Furthermore, the hair removal process is based on the same physical principles.
Ruben Herberht Mamani-Cato+5 more
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The itch sensation results from the excitation of primary sensory nerve endings in the skin, but the underlying molecular mechanisms are not completely understood. Liu et al. (2009) now report that some members of the Mrgpr class of G protein-coupled receptors mediate the itch caused by the antimalarial drug chloroquine.
Ardem Patapoutian+2 more
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Optimization of the treatment of patients with severe chronic urticaria
Severe chronic urticaria (SCU) is a common disease that burdens the lives of millions of people, reduces their quality of life, and imposes a significant economic burden not only on the health care system, but also directly on the patient.
Ye.M. Dytiatkovska, N.O. Nedohybchenko
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A quantitative analytical investigation on the oxycodone side effects listed in recent clinical trials [PDF]
Background: Oxycodone is a semi-synthetic narcotic analgesic medication with numerous side effects. Patients who use oxycodone may have one or more side effects depending on their clinical status and/or other factors.
Farshad Ghassemi Toosi+1 more
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