Results 251 to 260 of about 26,897,002 (317)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

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Item Analysis

Educational and Psychological Measurement, 2018
W. Holmes Finch, Brian F. French
semanticscholar   +3 more sources

Critical Item Analysis Enhances the Classification Accuracy of the Logical Memory Recognition Trial as a Performance Validity Indicator

Developmental Neuropsychology, 2021
Objective : Replicate previous research on Logical Memory Recognition (LM Recog ) and perform a critical item analysis. Method : Performance validity was psychometrically operationalized in a mixed clinical sample of 213 adults.
Alexa G. Dunn, Sadie R Pyne, Bradley T. Tyson, Robert Roth, A. Shahein, Laszlo A Erdodi   +5 more
semanticscholar   +1 more source

Using Full-information Item Analysis to Improve Item Quality

Educational Assessment, 2021
Full-information item analysis provides item developers and reviewers comprehensive empirical evidence of item quality, including option response frequency, point-biserial index (PBI) for distractors, mean-scores of respondents selecting each option, and
T. Haladyna, Michael C. Rodriguez
semanticscholar   +1 more source

Item Analysis

Encyclopedia of Autism Spectrum Disorders, 2021
Timothy Soto
openaire   +2 more sources

Item Analysis

The SAGE Encyclopedia of Research Design, 2010
openaire   +2 more sources