Results 141 to 150 of about 3,275,659 (305)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
C-Test construct validity: Evidence from nonparametric item response theory
Language Testing in AsiaC-Test is a gap-filling test designed to measure first and second language proficiency. Over the past four decades, researchers have shown the fit of C-Test data to parametric item response theory (IRT) models, but no study so far has shown the fit of C ...
Roya Shoahosseini +3 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Designer Spotlight: Patrick Kelly
The Museum at FIT presents its Designer Spotlight series where MFIT curators explore objects in our permanent collection that highlight a specific designer's work and contributions to fashion.Born in Mississippi in 1954, Patrick Kelly moved to Paris in ...
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ITA 2.0: A Program for Classical and Inductive Item Tree Analysis [PDF]
Item Tree Analysis (ITA) is an explorative method of data analysis which can be used to establish a hierarchical structure on a set of dichotomous items from a questionnaire or test.
Martin Schrepp
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Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
FIT Entrepreneurship Series: Dr. Joyce F. Brown and Norma Kamali
The FIT Foundation welcomes iconic designer, entrepreneur, and FIT alumna Norma Kamali to kick off its FIT Entrepreneurship Series with a conversation with Dr. Joyce F. Brown, president of FIT. The pair will discuss Kamali’s time at FIT, her more than 50
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FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Fashion Culture: From Louis Armstrong to Dizzy Gillespie: Jazz and Black Glamour
In a conversation moderated by MFIT assistant curator Elizabeth Way, historian Alphonso McClendon and vintage performer Dandy Wellington discuss the influence of jazz on 1920s fashion.
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