Results 121 to 130 of about 376,522 (308)

Application of Item Response Theory (IRT)-Graded Response Model (GRM) to Entrepreneurial Ecosystem Scale [PDF]

open access: gold, 2022
Waqar Ahmed Sethar   +5 more
openalex   +1 more source

Modeling Item-Level Data With Item Response Theory

open access: yesCurrent Directions in Psychological Science, 1998
ficult questions. Ideally, the two camps should have much cross fertilization, and the lines between them should be blurred. However, complex theories are often con structed before appropriate meth ods are developed for testing the hypotheses. Additionally, quanti tative psychologists often develop techniques that might be difficult and impractical to ...
openaire   +3 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Modeling variability in item parameters in item response models

open access: yes, 2001
In some areas of measurement item parameters should not be modeled as fixed but as random. Examples of such areas are: item sampling, computerized item generation, measurement with substantial estimation error in the item parameter estimates, and grouping of items under a common stimulus or in a common context.
Glas, Cornelis A.W.   +1 more
openaire   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

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