Results 131 to 140 of about 21,112,499 (262)
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Comparing performance of statistical models for individual’s ability index and ranking [PDF]
Efficient allocation of resources is the basic problem in economics. Firms, educational institutions, universities are faces problem of estimating true abilities and ranking of individuals to be selected for job, admissions and scholarship awards etc ...
Iqbal, Javed
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Extensions to Mean–Geometric Mean Linking
MathematicsMean-geometric mean (MGM) linking is a widely used method for linking two groups within the two-parameter logistic (2PL) item response model. However, the presence of differential item functioning (DIF) can lead to biased parameter estimates using the ...
Alexander Robitzsch
doaj +1 more source
Approximating Bifactor IRT True-Score Equating With a Projective Item Response Model. [PDF]
Appl Psychol Meas, 2020 Kim KY, Cho UH.
europepmc +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Item Response Theory Model for Understanding Item Non- Response in Ghanaian Surveys [PDF]
, 2014 This paper explores four Item Response Theory (IRT) models to determine the most appropriate forunderstanding item non-response. The selected IRT model was used to identify among five categories of surveyquestions, the most difficult to answer by ...
Amoamah, Martin Owusu +2 more
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InformationDifferential test functioning (DTF) assesses, within an item response model, whether differential item functioning (DIF) affects the test as a whole.
Alexander Robitzsch
doaj +1 more source
A Multiprocess Item Response Model for Not-Reached Items due to Time Limits and Quitting. [PDF]
Educ Psychol Meas, 2020 Ulitzsch E, von Davier M, Pohl S.
europepmc +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
The Italian Treasury Econometric Model (ITEM) [PDF]
In this paper, we provide a description of the Italian Treasury Econometric Model (ITEM). We illustrate its general structure and model properties, especially with regard to the economy's response to changes in policy and in other dimensions of the ...
Ottavio Ricchi +4 more
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