Results 131 to 140 of about 1,625,624 (298)

Hierarchical Compound Poisson Factorization

open access: yes, 2016
Non-negative matrix factorization models based on a hierarchical Gamma-Poisson structure capture user and item behavior effectively in extremely sparse data sets, making them the ideal choice for collaborative filtering applications. Hierarchical Poisson
Basbug, Mehmet E.   +1 more
core  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Modeling of Responses and Response Times with the Package cirt [PDF]

open access: yes
In computerized testing, the test takers' responses as well as their response times on the items are recorded. The relationship between response times and response accuracies is complex and varies over levels of observation.
Jean-Paul Fox   +2 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Employment of Item Response Theory to measure change in Children's Analogical Thinking Modifiability Test

open access: yesEstudos de Psicologia (Campinas)
Dynamic testing, with an intermediate phase of assistance, measures changes between pretest and post-test assuming a common metric between them. To test this assumption we applied the Item Response Theory in the responses of 69 children to dynamic ...
Odoisa Antunes de Queiroz   +3 more
doaj   +1 more source

Markov Chain Monte Carlo Estimation of Normal Ogive IRT Models in MATLAB [PDF]

open access: yes
Modeling the interaction between persons and items at the item level for binary response data, item response theory (IRT) models have been found useful in a wide variety of applications in various fields. This paper provides the requisite information and
Yanyan Sheng
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Bias-Reduced Haebara and Stocking–Lord Linking

open access: yesJ
Haebara and Stocking–Lord linking methods are frequently used to compare the distributions of two groups. Previous research has demonstrated that Haebara and Stocking–Lord linking can produce bias in estimated standard deviations and, to a smaller extent,
Alexander Robitzsch
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

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