Results 161 to 170 of about 12,669,314 (268)

Impact of Dupilumab Therapy on Skin Barrier Function in Patients With Moderate‐to‐Severe Atopic Dermatitis: A Phase IV, Non‐Randomized, Open‐Label, Parallel‐Group Clinical Study

MedComm, Volume 7, Issue 11, November 2026.
This 16‑week study assessed impact of dupilumab on skin barrier function in patients with moderate‑to‑severe atopic dermatitis (AD). Tape‑stripped stratum corneum samples for multi‑omic profiling, alongside transepidermal water loss measurements, were collected from lesional/non‑lesional AD skin and healthy controls at seven time points.
Taoming Liu, Shuting Chen, Weijia Zhao, Dake Di, Jiao Liu, Yuyang Tian, Yurong Luo, Yingping Xu, Ruzeng Xue, Li Ye, Xiaoping Pei, Bihui Yu, Yu Wang, Jiao Zhang, Xiaoling Yu, Wei Wen, Liyan Yuan, Suyun Ji, Claire Hu, Dan Shen, Yiqing Guo, Yunsheng Liang   +21 more
wiley   +1 more source

Longitudinal Modeling of Cardiometabolic Dysfunction in Patients With Type 2 Diabetes Using Item Response Theory

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 11, November 2026.
ABSTRACT Cardiometabolic dysfunction in patients with type 2 diabetes (T2D) is reflected by multiple risk factors and cannot be fully characterized by any single biomarker. Item response theory (IRT) provides a framework for integrating observed risk factors into latent measures of underlying cardiometabolic dysfunction.
Chengli Yu, Hanna Kunina, Gustaf J. Wellhagen, Maria C. Kjellsson   +3 more
wiley   +1 more source

Cultural and Linguistic Adaptation of Diagnostic Language Assessments: A Scoping Review

International Journal of Language &Communication Disorders, Volume 61, Issue 6, November/December 2026.
ABSTRACT Background Diagnostic language assessments are central to identifying developmental language disorder; however, many widely used tools were developed and normed within monolingual Western contexts. Their application in multilingual and multicultural settings raises concerns about linguistic, cultural and psychometric validity.
Mignon Botes, Khetsiwe Masuku, Anniah Mupawose   +2 more
wiley   +1 more source

Mapping Layers of Sustainability Consciousness in Food Consumption Using the Item Response Theory (IRT) Approach. [PDF]

J Food Sci
Bakucs Z, Baráth L, Benedek Z, Fertő I, Sipos L.   +4 more
europepmc   +1 more source

‘We're not going to start lifting stones now…’: Stakeholder perspectives on the role of psychometric methods in outcome measurement

British Journal of Clinical Psychology, Volume 65, Issue 4, Page 1232-1247, November 2026.
Abstract Objectives Psychological outcome measures guide research and clinical decision‐making, yet many widely used tools were developed with limited psychometric rigour. Although advanced methods (e.g., item response theory, structural equation modelling) are now widely available, their added value in applied research remains uncertain and applied ...
David Byrne, Fiona Boland, Susan Brannick, Robert M. Carney, Pim Cuijpers, Alexandra L. Dima, Kenneth E. Freedland, Suzanne Guerin, David Hevey, Bishember Kathuria, Emma Wallace, Frank Doyle   +11 more
wiley   +1 more source

Development and psychometric validation of the 8-item Student Quality of Life Index (IQoL) using item response theory (IRT): a cross-sectional study among Brazilian higher education students. [PDF]

BMJ Open
Gobbo M, Silveira de Resende M, Santos IM, Moura EC, Pedro RA.   +4 more
europepmc   +1 more source

Relations among daily symptoms of depression

British Journal of Psychology, Volume 117, Issue 4, Page 1432-1448, November 2026.
Abstract Research has often treated depression as a unitary construct, relying on severity scores or diagnostic thresholds; however, recent studies emphasize that depression is a heterogeneous disorder characterized by dynamic symptom interactions. We aimed to identify unique relations among depressive symptoms when examined longitudinally.
Meghan E. Quinn, Mary E. Kleinman, John P. Standring, Qimin Liu   +3 more
wiley   +1 more source

Reliability measures in knowledge structure theory

British Journal of Mathematical and Statistical Psychology, Volume 79, Issue 3, Page 457-478, November 2026.
Abstract In knowledge structure theory (KST) framework, this study evaluates the reliability of knowledge state estimation by introducing two key measures: the expected accuracy rate and the expected discrepancy. The accuracy rate quantifies the likelihood that the estimated knowledge state aligns with the true state, while the expected discrepancy ...
Debora de Chiusole, Andrea Spoto, Umberto Granziol, Luca Stefanutti   +3 more
wiley   +1 more source

The Vaccination Fear Scale (VFS-6): Adaptation, Cross-Cultural Validation, and Invariance among Genders and Six Different Cultures, Applying Classical Test Theory (CTT) and Item Response Theory (IRT). [PDF]

Eur J Investig Health Psychol Educ
Malas O, Boustani NM, Duradoni M, Omotoso D, Avşar AŞ, Shyroka A, Colombini G, Blanch A.   +7 more
europepmc   +1 more source

Using item response theory (IRT) to reduce patient burden when assessing desire for hastened death. [PDF]

Psychol Assess, 2017
Kolva E, Rosenfeld B, Liu Y, Pessin H, Breitbart W.   +4 more
europepmc   +1 more source