Results 41 to 50 of about 17,628 (268)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Fractals of Interpolative Kannan Mappings

Fractal and Fractional
In 2018, Erdal Karapinar introduced the concept of interpolative Kannan operators, a novel adaptation of the Kannan mapping originally defined in 1969 by Kannan. This new mapping condition is more lenient than the basic contraction condition.
Xiangting Shi, Umar Ishtiaq, Muhammad Din, Mohammad Akram   +3 more
doaj   +1 more source

On Weakly Hyperbolic Iterated Function Systems

Bulletin of the Brazilian Mathematical Society, New Series, 2016
Updated version.
Arbieto, Alexander, Junqueira, André, Santiago, Bruno   +2 more
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

The Generalized Iterated Function System and Common Attractors of Generalized Hutchinson Operators in Dislocated Metric Spaces

Fractal and Fractional, 2023
In this paper, we present the generalized iterated function system for the construction of common fractals of generalized contractive mappings in the setup of dislocated metric spaces.
Talat Nazir, Sergei Silvestrov
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

On Product Neutrosophic Fractal Spaces and α-Density Theory with Arbitrarily Small and Controlled Error

Fractal and Fractional
In this manuscript, we present the classical Hutchinson–Barnsley theory on the product neutrosophic fractal spaces by utilizing an iterated function system, which is enclosed by neutrosophic Edelstein contractions and a finite number of neutrosophic b ...
Khaleel Ahmad, Umar Ishtiaq, Ghulam Murtaza, Ioan-Lucian Popa, Fethi Mohamed Maiz   +4 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Arcwise connected attractors of infinite iterated function systems

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2014
The aim of this paper is to give a sufficient condition for the attractor of an infinite iterated function system to be arcwise connected.
Dumitru Dan
doaj   +1 more source