Results 61 to 70 of about 21,370,789 (250)
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Oyun: A New, Free Program for Iterated Prisoner’s Dilemma Tournaments in the Classroom [PDF]
Evolutionary applications of game theory present one of the most pedagogically accessible varieties of genuine, contemporary theoretical biology. We present here Oyun (OY-oon, http://charlespence.net/oyun), a program designed to run iterated prisoner’s ...
Charles H. Pence +4 more
core +2 more sources
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
On Bounding Boxes of Iterated Function System Attractors
[[abstract]]Before rendering 2D or 3D fractals with iterated function systems, it is necessary to calculate the bounding extent of fractals. We develop a new algorithm to compute the bounding box which closely contains the entire attractor of an iterated
H. T. Chu ; C. C. Chen
core
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Common Attractors of Generalized Hutchinson–Wardowski Contractive Operators
The aim of this paper is to obtain a fractal set of ℑ-iterated function systems comprising generalized ℑ-contractions. For a variety of Hutchinson–Wardowski contractive operators, we prove that this kind of system admits a unique common attractor ...
Bilal Iqbal +3 more
doaj +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
On bounding boxes of iterated function system attractors
[[abstract]]Before rendering 2D or 3D fractals with iterated function systems, it is necessary to calculate the bounding extent of fractals. We develop a new algorithm to compute the bounding box which closely contains the entire attractor of an iterated
Chu, HT;Chen, CC
core +1 more source
Multi Fuzzy Fractal Theorems in Fuzzy Metric Spaces
The Hutchinson-Barnsley (HB) operators are studied for multi iterated function system in a general setting. Some existence and uniqueness results are obtained in fuzzy fractal and multi fuzzy fractal spaces.
B. Prasad, K. Katiyar
doaj +1 more source
On the Bernstein Affine Fractal Interpolation Curved Lines and Surfaces
In this article, firstly, an overview of affine fractal interpolation functions using a suitable iterated function system is presented and, secondly, the construction of Bernstein affine fractal interpolation functions in two and three dimensions is ...
Nallapu Vijender, Vasileios Drakopoulos
doaj +1 more source

