Results 151 to 160 of about 321,959 (297)
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Emotional responses to naturalistic and artificial intelligence (AI)-generated affective pictures: A systematic comparison. [PDF]
EmotionGilbert F +8 more
europepmc +1 more source
Safe policy iteration : a monotonically improving approximate policy iteration approach
, 2012 LAUREA MAGISTRALEThis thesis provides a study of the policy improvement step that can be usefully exploited by approximate policy–iteration algorithms. While the exact policy iteration approach is guaranteed to improve the performance of the policy at ...
PIROTTA, MATTEO, PECORINO, ALESSIO
core
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Development of conditional cores via supersaturated designs for genetic diversity-based prediction models. [PDF]
Plant GenomeZhou X, Garcia-Abadillo J, Jarquin D.
europepmc +1 more source
, 2015 [[abstract]]In this paper, we introduce the concept of generalized pseudo-contractive and generalized hemi-contractive mappings, and study the strong con- vergence theorems for approximation of common ¯xed points of gener- alized hemi-contractive ...
Hu, Thakyin(胡德軍), Huang, Jui-chi
core
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
From forward-backward sweep to backpropagation for optimal control in tumor-immune dynamics. [PDF]
J Math BiolZhang W, Ding W, Zhu H.
europepmc +1 more source