Iterative development of a pediatric point-of-care ultrasound training program. [PDF]
Kerenyi A +5 more
europepmc +1 more source
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett +7 more
wiley +1 more source
Fixed point approximation for generalized μ-Reich-Suzuki nonexpansive mappings with application. [PDF]
Ishtiaq T +3 more
europepmc +1 more source
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni +7 more
wiley +1 more source
Novel iterative method for the approximation of fixed point of a class of generalized ([Formula: see text])-nonexpansive mapping with applications to seir epidemic model. [PDF]
Alharthi NH +4 more
europepmc +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
An Unsupervised Image Stitching Framework via Joint Iterative Optimization of Deformation Estimation, Feature Registration, and Seamless Blending. [PDF]
Ning B +5 more
europepmc +1 more source
Microengineered Gradient Hydrogels for Mechanobiology
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong +4 more
wiley +1 more source
Magnetic Heterodyne Target Proximal Distance Estimate Using Extended N-th-Pole Magnetic Dipole Model via Iterative Extended Kalman Filter. [PDF]
Miao X +6 more
europepmc +1 more source
ABSTRACT In vitro arterial models offer ethical and robust alternatives for vascular research but require cytocompatible materials that replicate physiological mechanics. Poly(vinyl alcohol) (PVA) hydrogels produced by directional freezing and salting‐out (PVA DFSO) are anisotropic yet lack stability for cell culture. Herein, methacrylated PVA (PVA‐MA)
Javiera Sanhueza Ortega +4 more
wiley +1 more source

