Results 71 to 80 of about 296,284 (267)
ABSTRACT Objective Autosomal dominant progranulin (GRN) pathogenic variants are a genetic cause of frontotemporal lobar degeneration. Though clinical trials for GRN‐related therapies are underway, there is an unmet need for biomarkers that can predict symptom onset and track disease progression.
Taru M. Flagan +46 more
wiley +1 more source
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin +12 more
wiley +1 more source
On a computer implementation of the block Gauss-Seidel method for normal systems of equations
This article focuses on the modification of the block option Gauss-Seidel method for normal systems of equations, which is a sufficiently effective method of solving generally overdetermined, systems of linear algebraic equations of high dimensionality ...
Alexander I Bogdanova +1 more
doaj +1 more source
Iterative learning control for constrained linear systems [PDF]
This paper considers iterative learning control for linear systems with convex control input constraints. First, the constrained ILC problem is formulated in a novel successive projection framework.
Chu, B., Owens, D.H.
core
Objective We assessed whether shared decision‐making (SDM), and patient acceptability, feasibility, and overall satisfaction with a computerized patient decision aid (PtDA) for patients with systemic lupus erythematosus (SLE), differs by PtDA setting, modality, and the viewing experience.
Jasvinder A. Singh +3 more
wiley +1 more source
A numerical approach is proposed for solving multidimensional parabolic diffusion and hyperbolic wave equations subject to the appropriate initial and boundary conditions. The considered numerical solutions of the these equations are considered as linear
Bashar Zogheib +2 more
doaj +1 more source
Background In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of a scleroderma patient's ...
Ji Soo Kim +18 more
wiley +1 more source
A Bramble-Pasciak conjugate gradient method for discrete Stokes equations with random viscosity
We study the iterative solution of linear systems of equations arising from stochastic Galerkin finite element discretizations of saddle point problems. We focus on the Stokes model with random data parametrized by uniformly distributed random variables ...
Lang, Jens +2 more
core +1 more source
Objectives Australian evidence on lived and care experiences of chronic musculoskeletal shoulder pain (CMSP), irrespective of disorder classification or disease, is limited. However, such evidence is important for person‐centred care and informing local service pathways and care guidelines or standards.
Sonia Ranelli +8 more
wiley +1 more source
Study of methods for dimension reduction of complex dynamic linear systems models
Complex dynamic linear systems of equations are solved by numerical iterative methods, which need much computation and are timeconsuming ones, and the optimization stage requires repeated solution of these equation systems that increases the time on ...
Manatskov Yuriy M. +3 more
doaj +1 more source

