Results 51 to 60 of about 308,108 (251)
, 1998 We propose an efficient numerical algorithm for solving integral equations of the theory of liquids in the Reference Interaction Site Model (RISM) approximation for infinitely dilute solution of macromolecules with a large number of atoms.
A. V. Gorelov +10 more
core +1 more source
Low-Complexity Numerical Approach for the Diffusion Equation with Variable Diffusion Coefficient
MathematicsThe diffusion equation models a wide variety of physical and chemical processes and has significant interest in many scientific disciplines. Analytical and numerical methods found in the literature for solving the diffusion equation consider a constant ...
Marta Zárraga-Rodríguez +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
On Improving Computational Efficiency of Simplified Fluid Flow Models
Chemical Engineering Transactions, 2018 Single-core computational efficiency of several iterative methods for numerical solution of nonsymmetric linear systems originating from simplified fluid flow models is evaluated together with different preconditioning techniques in terms of solution ...
Vojtech Turek
doaj +1 more source
Gradient Hard Thresholding Pursuit for Sparsity-Constrained Optimization [PDF]
, 2013 Hard Thresholding Pursuit (HTP) is an iterative greedy selection procedure for finding sparse solutions of underdetermined linear systems. This method has been shown to have strong theoretical guarantee and impressive numerical performance. In this paper,
Li, Ping, Yuan, Xiao-Tong, Zhang, Tong
core
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
An Efficient Sixth-Order Newton-Type Method for Solving Nonlinear Systems
Algorithms, 2017 In this paper, we present a new sixth-order iterative method for solving nonlinear systems and prove a local convergence result. The new method requires solving five linear systems per iteration.
Xiaofeng Wang, Yang Li
doaj +1 more source
A randomized Kaczmarz algorithm with exponential convergence
, 2007 The Kaczmarz method for solving linear systems of equations is an iterative algorithm that has found many applications ranging from computer tomography to digital signal processing.
Strohmer, Thomas, Vershynin, Roman
core +2 more sources