Results 51 to 60 of about 24,096 (281)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

A generalized preconditioned MHSS method for a class of complex symmetric linear systems

open access: yesMathematical Modelling and Analysis, 2013
Based on the MHSS (Modified Hermitian and skew-Hermitian splitting) and preconditioned MHSS methods, we will present a generalized preconditioned MHSS method for solving a class of complex symmetric linear systems.
Mehdi Dehghan   +2 more
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

OpenFOAM iterative methods efficiency analysis for linear systems solving

open access: yesТруды Института системного программирования РАН, 2018
Significant part of the computational work in numerical simulations of technical systems, physical phenomena and technological processes is solving of linear algebraic equations systems arising from the discretization of the corresponding differential or
I. K. Marchevsky, V. V. Puzikova
doaj  

A Preconditioned Iterative Approach for Efficient Full Chip Thermal Analysis on Massively Parallel Platforms

open access: yesTechnologies, 2018
Efficient full-chip thermal simulation is among the most challenging problems facing the EDA industry today, especially for modern 3D integrated circuits, due to the huge linear systems resulting from thermal modeling approaches that require unreasonably
George Floros   +3 more
doaj   +1 more source

A proposal for an instructional methodological class on iterative numerical methods for Systems of Linear Equations

open access: yesGamification and Augmented Reality
Introduction: The methodological work aimed to enhance teachers' pedagogical preparation to optimize the teaching-learning process, focusing on improving Curriculum E of Computer Science, specifically in the Numerical Mathematics course.  Methods: An instructional methodological class was designed based on previous research conducted at the Faculty of ...
Damian Valdés Santiago   +1 more
openaire   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

The Faber polynomials for annular sectors and an application to the iterative solution of linear systems of equations [PDF]

open access: yes, 1994
A conformal mapping of the exterior of the unit circle to the exterior of a region of the complex plane determines the Faber polynomials for that region.
Myers, Nicholas John, Myers, N.J
core  

Feedback methods for inverse simulation of dynamic models for engineering systems applications [PDF]

open access: yes, 2011
Inverse simulation is a form of inverse modelling in which computer simulation methods are used to find the time histories of input variables that, for a given model, match a set of required output responses.
David J. Murray-Smith   +1 more
core   +1 more source

Low-Complexity Numerical Approach for the Diffusion Equation with Variable Diffusion Coefficient

open access: yesMathematics
The diffusion equation models a wide variety of physical and chemical processes and has significant interest in many scientific disciplines. Analytical and numerical methods found in the literature for solving the diffusion equation consider a constant ...
Marta Zárraga-Rodríguez   +2 more
doaj   +1 more source

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