Results 51 to 60 of about 173,139 (267)

H2/H∞ output information-based disturbance attenuation for differential linear repetitive processes [PDF]

open access: yes, 2010
Repetitive processes propagate information in two independent directions where the duration of one is finite. They pose control problems that cannot be solved by application of results for other classes of 2D systems.
Paszke, Wojtek   +5 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

On control laws for discrete linear repetitive processes with dynamic boundary conditions [PDF]

open access: yes, 2008
Repetitive processes are characterized by a series of sweeps, termed passes, through a set of dynamics defined over a finite duration known as the pass length.
Rogers, E   +7 more
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

H/sub /spl infin// control of differential linear repetitive processes [PDF]

open access: yes, 2006
—Repetitive processes are a distinct class of two-dimensional (2-D) systems (i.e., information propagation in two independent directions) of both systems theoretic and applications interest.
Paszke, W.   +3 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Comments on 'On the equivalence of causal LTI iterative learning control and feedback control [PDF]

open access: yes, 2004
The area of Iterative Learning Control (ILC) now has a large and increasing body of research with an increasing number of applications (supported by a sizable number of actual experimental verification studies). The paper by Goldsmith (Automatica, 38, pp.
Owens, D H, Rogers, E
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

A Behavioral Approach to the Control of Discrete Linear Repetitive Processes [PDF]

open access: yes, 2004
This paper formulates the theory of linear discrete time repetitive processes in the setting of behavioral systems theory. A behavioral, latent variable model for repetitive processes is developed and for the physically defined inputs and outputs as ...
Rogers, E, Sule, V R, SULE, VR
core   +1 more source

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