Iterative Reconstruction of Micro Computed Tomography Scans Using Multiple Heterogeneous GPUs. [PDF]
Chou WH, Wu CH, Jin SC, Chen JC.
europepmc +1 more source
Genome‐wide codon reprogramming of influenza A virus introduces 1956 synonymous mutations across five segments and elevates CpG content, causing defective NA packaging, loss of NS1 accumulation, and enhanced ZAP‐mediated antiviral responses without affecting RNA or protein synthesis. These mechanisms result in profound attenuation and potent homologous
Yang Wang +13 more
wiley +1 more source
Evaluation of Low-dose Computed Tomography Images Reconstructed Using Artificial Intelligence-based Adaptive Filtering for Denoising: A Comparison with Computed Tomography Reconstructed with Iterative Reconstruction Algorithm. [PDF]
Kulkarni S +8 more
europepmc +1 more source
Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv +29 more
wiley +1 more source
Solid Harmonic Wavelet Bispectrum for Image Analysis
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown +3 more
wiley +1 more source
Coronary CT angiography: First comparison of model-based and hybrid iterative reconstruction with the reference standard invasive catheter angiography for CAD-RADS reporting. [PDF]
Matuleviciute-Stojanoska A +6 more
europepmc +1 more source
A non-iterative reconstruction method for direct and unambiguous coherent diffractive imaging
S. G. Podorov +2 more
openalex +1 more source
Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi +21 more
wiley +1 more source
Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao +8 more
wiley +1 more source
Model-based iterative reconstruction for direct imaging with point spread function encoded echo planar MRI. [PDF]
Meyer NK +8 more
europepmc +1 more source

