Results 261 to 270 of about 257,977 (271)

Genome‐scale Metabolic Modeling Guided Escherichia coli Engineering for De Novo Biosynthesis of Chrysanthemic Acid

Advanced Science, EarlyView.
Genome‐scale metabolic modeling is preceded to the engineered E. coli cell factory for the de novo biosynthesis of biopesticide chrysanthemic acid. The debranching strategy redirects metabolic flux, enhancing precursor and target compound production.
Jiangpeng Yu, Kelin Cheng, Shenyang Qu, Jie Wang, Xun Wang, Cheng Zhao, Wei Li   +6 more
wiley   +1 more source

A comparative analysis of deep learning and hybrid iterative reconstruction algorithms with contrast-enhancement-boost post-processing on the image quality of indirect computed tomography venography of the lower extremities. [PDF]

BMC Med Imaging
Du H, Sui X, Zhao R, Wang J, Ming Y, Piao S, Wang J, Ma Z, Wang Y, Song L, Song W.   +10 more
europepmc   +1 more source

SpaBalance: Balanced Learning for Efficient Spatial Multi‐Omics Decoding

Advanced Science, EarlyView.
SpaBalance is a computational framework that harmonizes multi‐omics learning via gradient equilibrium and dual‐stream feature decomposition, achieving superior clustering accuracy, biological interpretability, and scalable integration of three or more spatial omics modalities.
Yingbo Cui, Yong Zhao, Canqun Yang, Tao Tang, Xiangke Liao, Hongyu Zhang, Huiying Zhao, Zheng Wang, Yuansong Zeng   +8 more
wiley   +1 more source

A Dynamic Gate Enables Regioselective Hydroxylation of Free Arginine by a Non‐Canonical Heme Enzyme

Advanced Science, EarlyView.
The YqcI/YcgG enzyme AglA employs a unique “sandwich” fold and a dynamic gating mechanism to selectively hydroxylate AMPn‐Arg at Nε. Site‐directed mutations reprogram regioselectivity or enable activity on free arginine by altering hydrogen‐bond networks, precisely positioning substrates.
Yuan Sun, Chao Dou, Weizhu Yan, Pengpeng Chen, Lu Zhang, Dan Zhou, Yanhui Zheng, Zhaolin Long, Shoujie Li, Xiaoqing Xu, Qiuxia Huang, Xiaofeng Zhu, Wei Cheng   +12 more
wiley   +1 more source

DNA Origami and Its Applications in Synthetic Biology

Advanced Science, EarlyView.
This review provides a comprehensive summary of recent advancements in DNA origami for synthetic biology, emphasizing two key areas: the precise construction and dynamic regulation of extracellular‐to‐intracellular, and the synergistic integration with cell‐free systems.
Yaning Fang, Xuexin Chen, Qingsheng Qi, Min Lin, Quanfeng Liang   +4 more
wiley   +1 more source

A comparative study of low voltage, low contrast cerebral computed tomography angiography with iterative reconstruction and conventional cerebral computed tomography angiography. [PDF]

Neuroradiol J
Mishra S, Mishra S, Regmi S, Gupta V.
europepmc   +1 more source

A paradigm shift in oncology imaging: a prospective cross-sectional study to assess low-dose deep learning image reconstruction versus standard-dose iterative reconstruction for comprehensive lesion detection in dual-energy computed tomography. [PDF]

Quant Imaging Med Surg
Hou P, Liu N, Feng X, Chen Y, Wang H, Wang X, Liu J, Zhan P, Liu X, Shang B, Shen Z, Wang L, Gao J, Lyu P.   +13 more
europepmc   +1 more source

Nonenhanced Photon Counting CT of the Head : Impact of the keV Level, Iterative Reconstruction and Calvaria on Image Quality in Monoenergetic Images. [PDF]

Clin Neuroradiol
Michael AE, Schoenbeck D, Woeltjen MM, Boriesosdick J, Kroeger JR, Moenninghoff C, Horstmeier S, Niehoff JH, Kabbasch C, Goertz L, Borggrefe J.   +10 more
europepmc   +1 more source

Iterative Residual Optimization Network for Limited-Angle Tomographic Reconstruction

Jiayi Pan, Hengyong Yu, Zhifan Gao, Shaoyu Wang, Heye Zhang, Weiwen Wu   +5 more
openalex   +1 more source