Results 31 to 40 of about 6,495 (256)
Les itinéraires parisiens du commissaire Maigret
Géographie et Cultures, 2007 Space is important in Georges Simenon’s novels, especially in the detective stories where commissaire Maigret likes to stroll through the streets of Paris.
Dominique Meyer‑Bolzinger
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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Amor sapientiae w itinerarium duchowym św. Augustyna
Studia Koszalińsko-Kołobrzeskie, 2020 The article shows the most characteristic elements of the teaching of St. Augustine on the subject of amor sapientiae. It represents a synthetic analysis, based on statements from the whole life of a thinker from Thagaste.
Sylwester Jaśkiewicz
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IEEE Access, 2022 The tourist trip design problem (TTDP) helps the trip planners, such as tourists, tour companies, and government agencies, automate their trip planning. TTDP solver chooses and sequences an optimal subset of point of interest (POIs), which adhere to the ...
Supoj Choachaicharoenkul +2 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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TOWARDS ENHANCED PLANNING OF URBAN TRANSPORT IN ALGERIA: STRATEGIES FOR IMPROVEMENT IN THE CITY OF BOUIRA [PDF]
Geo Journal of Tourism and GeositesThis research focuses on the functioning of urban transport in Bouira and examines the difficulties that affect daily mobility. The study evaluates how routes are organized, how services are delivered, and how users perceive the system.
Hocine AMICHI +2 more
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
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Therapeutic itinerary of severe malaria in adults admitted to a teaching hospital in Dakar, Senegal
Journal of Infection in Developing Countries, 2014 Introduction: Despite prevention efforts, malaria remains a public health problem. Methodology: This was a prospective study conducted between October and December 2010 that aimed to describe the therapeutic route of adults presenting with severe ...
Sylvie Audrey Diop +4 more
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
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EVALUATION OF EFFECTS OF INTRODUCING A CONTACTLESS FARE PAYMENT SYSTEM ON URBAN PASSENGER TRANSPORT
Дискурс, 2016 The article is devoted to identifying the effects of introducing contactless payment systems (BSOP) travel on urban passenger transport, study their complex manifestations, assessment of possible synergistic effects of implementing capacity, estimation ...
E. V. Budrina
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