Results 101 to 110 of about 45,170 (249)

Avatrombopag for persistent and chronic immune thrombocytopenia in children: A post hoc analysis of clinical characteristics of response from a phase 3b clinical trial

British Journal of Haematology, EarlyView.
Summary Avatrombopag treatment resulted in significantly higher platelet response rates in patients when compared with placebo in a phase 3b study of patients with paediatric immune thrombocytopenia (ITP) (NCT04516967). These post hoc analyses of the 12‐week core phase further assessed the efficacy of avatrombopag, considering the influence of baseline
Rachael F. Grace, Göksel Leblebisatan, Yesim Aydinok, Sule Unal, John Grainger, Amanda B. Grimes, Michele P. Lambert, Jessica Zhang, Brian D. Jamieson, Faizan Sattar, Scott Kolodny, Michael Vredenburg, on behalf of the AVA‐PED‐301 Study Group   +12 more
wiley   +1 more source

Efficacy and safety of Privigen, a novel liquid intravenous immunoglobulin formulation, in adolescent and adult patients with chronic immune thrombocytopenic purpura.

, 2009
Intravenous immunoglobulin (IVIG) has become a mainstay of treatment for acute and chronic immune thrombocytopenic purpura (ITP). The efficacy and safety of Privigen, a new, ready-to-use, 10% liquid human IgG formulation, was evaluated in this open-label,
DAVIES SV, SALAMA A, ZENKER O, MAZZUCCONI, Maria Gabriella, VYHOVSKA Y, INTERNATIONAL PRIVIGEN IN ITP STUDY GROUP, ROBAK T, KOVALEVA L, KIESSLING P   +8 more
core   +1 more source

Role of Platelet indices as surrogate markers for bone marrow activity in newly diagnosed ITP and chronic ITP [PDF]

, 2020
BACKGROUND: In Immune Thrombocytopenia, newly diagnosed patients tend to have adequate, compensatory Bone Marrow response, by producing megakaryocytes in adequate numbers, which reflects an increase in Mean Platelet Volume, Platelet Larger Cell Ratio ...
Sivakumar, G
core  

Immune Thrombocytopenia Relapse in Patients Who Received mRNA COVID-19 Vaccines

Journal of Blood Medicine, 2023
Hana Qasim,1,2 Alaa Rahhal,3 Ahmed Husain,4 Abdelkarim Alammora,5 Khaled Alsa’ed,5 Ahmed Abdelghafar Masaad Alsayed,5 Baha Faiyoumi,5 Leen Maen AbuAfifeh,5 Mohammad Abu-Tineh,1 Awni Alshurafa,1 Mohamed A Yassin1 1Hematology-Oncology Department, National ...
Qasim H, Rahhal A, Husain A, Alammora A, Alsa’ed K, Alsayed AAM, Faiyoumi B, Maen AbuAfifeh L, Abu-Tineh M, Alshurafa A, Yassin MA   +10 more
doaj  

From haemostasis to immunity: The expanding frontiers of platelet biology

British Journal of Haematology, EarlyView.
Platelets are versatile cells whose functions extend far beyond haemostasis and thrombosis, actively regulating innate and adaptive immunity, angiogenesis, lymphangiogenesis, liver regeneration, atherosclerosis and tumour metastasis. This demonstrates their central role in various physiological processes and multiple life‐threatening diseases ...
Xun Grace Wu, Nicole Tomei, Heyu Ni
wiley   +1 more source

The ‘T’ in ITP remains

Cleveland Clinic Journal of Medicine, 2012
The “I” has changed its meaning and the “P” is not necessary to make the diagnosis, but the disease formerly known as idiopathic thrombocytopenic purpura (ITP) remains important to diagnose.
openaire   +2 more sources

The association between inborn errors of immunity and Hodgkin lymphoma—A register‐based case–control study in Sweden

British Journal of Haematology, EarlyView.
Summary Immune dysfunction is implicated in the aetiology of Hodgkin lymphoma (HL), but the association between inborn errors of immunity (IEI) and HL remains poorly understood. We conducted a retrospective, register‐based case–control study in Sweden over five decades to investigate the relationship between IEI and HL. Individuals diagnosed with HL in
Agnes Winsa, Ingemar Lagerlöf, Fredrik Ellin, Mats Fredriksson, Åsa Nilsdotter‐Augustinsson, Marcus Bendtsen, Jörg Cammenga, Sofia Nyström   +7 more
wiley   +1 more source

ITP regulates water homeostasis.

, 2018
(A) Short term (6 h) desiccation stress efficiently reduces body fluids. Two-tailed Student’s t–test: P ITP gene. A primer pair that detects all 5 isoforms (transcripts RC, RD, RE, RF and RG, FlyBase FB2017_06) was used. Two-tailed Student’s t–test: P RE
Martina Gáliková (3274566), Dick R. Nässel (46701), Heinrich Dircksen (131005)   +2 more
core   +1 more source

The Differences between Pre- and Post-Therapy Levels of Platelet Count and Platelet Indices in Children with Immune Thrombocytopenia Purpura

Folia Medica Indonesiana
Highlights: 1. This study was the first to analyze the therapeutic response in children with ITP at Dr. Soetomo General Academic Hospital, Surabaya. 2. This study analyzed the response of platelet count and indices, including MPV, PDW, P-LCR, and PCT to ...
Regina Rania Cahya Kusumaningrum -, Mia Ratwita Andarsini, Yetti Hernaningsih, Pradana Zaky Romadhon   +3 more
doaj   +1 more source

Increased anergic B cells and decreased antibody‐secreting cells during romiplostim treatment in patients with immune thrombocytopenia

British Journal of Haematology, EarlyView.
Summary Patients with immune thrombocytopenia (ITP) exhibit substantial heterogeneity in treatment responses. Approximately 30%–50% of patients maintain remission after discontinuation of thrombopoietin receptor agonists (TPO‐RA), suggesting immunomodulatory effects beyond enhanced thrombopoiesis.
Vivianne S. Nelson, Rebeca Gutiérrez‐Cózar, Rebecca Cornelis, S. Marieke van Ham, Anja ten Brinke, Rick Kapur   +5 more
wiley   +1 more source