Results 231 to 240 of about 41,330 (277)

The function of T cells in immune thrombocytopenia. [PDF]

Front Immunol
Bu S, Liu M, Yang L, Lee P, Miller H, Park CS, Byazrova M, Filatov A, Benlagha K, Gaber T, Buttgereit F, Gong Q, Zhai Z, Liu C.   +13 more
europepmc   +1 more source

Efficacy and safety analysis of China's first 10% IVIg (RonsenGlob) therapy in treating adult ITP. [PDF]

Ann Hematol
Fang L, Sun T, Zhou H, Jie G, Fu J, Yang E, Zhou Z, Liu L, Zhang J, Qian S, Chen Y, Liu L, Gu J, Kong F, Huang R, Chen Y, Zhang L.   +16 more
europepmc   +1 more source

An update on pediatric ITP: differentiating primary ITP, IPD, and PID

Blood, 2022
AbstractImmune thrombocytopenia (ITP) is the most common acquired thrombocytopenia in children and is caused by immune-mediated decreased platelet production and increased platelet destruction. In the absence of a diagnostic test, ITP must be differentiated from other thrombocytopenic disorders, including inherited platelet disorders.
Rachael F. Grace, Michele P. Lambert
openaire   +4 more sources

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ITP-Pred: an interpretable method for predicting, therapeutic peptides with fused features low-dimension representation

Briefings Bioinform., 2020
The peptide therapeutics market is providing new opportunities for the biotechnology and pharmaceutical industries. Therefore, identifying therapeutic peptides and exploring their properties are important. Although several studies have proposed different
Lijun Cai, Li Wang, Xiangzheng Fu, Chenxing Xia, Xiangxiang Zeng, Q. Zou   +5 more
semanticscholar   +1 more source

Managing ITP and thrombocytopenia in pregnancy

Platelets, 2020
Around 1 in 10 pregnant women will develop thrombocytopenia during an otherwise unremarkable pregnancy. While the most frequent cause is gestational thrombocytopenia, a benign clinical entity which typically induces a mild platelet fall in late pregnancy,
R. Eslick, C. McLintock
semanticscholar   +1 more source

Immune Thrombocytopenia (ITP) in a Pediatric Patient Positive for SARS-CoV-2

Pediatrics, 2020
Immune thrombocytopenia (ITP) is a potential presentation of COVID-19. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral testing should be considered in these patients to allow for appropriate hospital triaging and isolation to limit ...
Hoi See Tsao, Hannah M. Chason, Deirdre M. Fearon   +2 more
semanticscholar   +1 more source

ITP: a historical perspective

British Journal of Haematology, 2011
SummaryA clinical syndrome of bleeding and purpura consistent with a diagnosis of immune thrombocytopenia (ITP) was described by Werlhof long before platelets were identified as the cellular component of blood playing an essential role in primary haemostasis.
Adrian C. Newland, Roberto Stasi
openaire   +3 more sources

Autoantibodies in chronic ITP

Blut, 1989
Chronic ITP is a syndrome of destructive thrombocytopenia due in most cases to antiplatelet autoantibodies. In the present studies we have studied 74 patients with chronic ITP using a new immunobead assay. Of these, 59 (79.7%) had demonstrable platelet-associated autoantibodies: 48 against platelet glycoprotein IIb/IIIa and 11 against glycoprotein Ib ...
Peter Berchtold, Robert McMillan, P Tani
openaire   +3 more sources

STIMULATED MEGAKARYOCYTES ARE FOUND IN CHILDHOOD ITP BUT NOT IN ADULT ITP [PDF]

Thrombosis and Haemostasis, 1987
ITP is thought to be caused primarily by peripheral platelet destruction, but recent work has suggested that platelet production may also be impaired. Although the clinical course in children usually differs from that in adults, no distinctions have been established with regard to marrow characteristics.
R F Levine, P K Shoff
openaire   +1 more source

Prevention of chronic ITP? [PDF]

Blut, 1989
The treatment of childhood ITP with IVIG has been widely used in acute or in previously treatment-dependent, chronic forms of the disease. We discuss propositions of a prospective multicenter study to evaluate the efficacy of IVIG to prevent the development of chronic ITP in childhood. The problems of such a study, i.e.
Brigitta U. Müller, Paul Imbach
openaire   +2 more sources