Results 31 to 40 of about 45,013 (259)
Novel Therapies to Address Unmet Needs in ITP
, 2022 Primary immune thrombocytopenia (ITP) is an autoimmune disorder that causes low platelet counts and subsequent bleeding risk. Although current corticosteroid-based ITP therapies are able to improve platelet counts, up to 70% of subjects with an ITP ...
Bastida, José María +7 more
core +1 more source
Platelets, 2020 MicroRNAs (miRNAs) are small non-coding RNAs involved in the regulation of gene expression. Dysregulated expression of several miRNAs has been found in primary immune thrombocytopenia (ITP) suggesting that miRNAs are likely involved in the pathogenesis ...
Lamya Garabet +9 more
doaj +1 more source
Thrombocytopenia induced by clopidogrel: a rare adverse effect
European Journal of Case Reports in Internal Medicine, 2023 Introduction: Immune thrombocytopenic purpura (ITP) can be induced by several drugs but there are few case reports of ITP induced by clopidogrel. Second-line treatment with thrombopoietin receptor agonists (TPO-RA) presents solid evidence and should be ...
Catarina Távora +2 more
doaj +1 more source
Complement in immune thrombocytopenia (ITP): The role of complement in refractory ITP
British Journal of Haematology, 2023 SummaryImmune thrombocytopenia (ITP) is a disorder characterized by low platelets due to increased clearance and decreased platelet production. While ITP has been characterized as an acquired disorder of the adaptive immune system, the resulting platelet autoantibodies provide ancillary links to the innate immune system via antibody interaction with ...
Ilene Ceil Weitz, Howard Allen Liebman
openaire +2 more sources
Angewandte Chemie, EarlyView.Coarse‐grained (CG) molecular dynamics simulations were used to predict the upper critical solution temperature of copolymers obtained by radical ring‐opening copolymerization of cyclic ketene acetals and vinyl monomers, and to account for their unique degradation kinetics under physiological conditions by evaluating the solvation of their ester groups.
Ping Gao +3 more
wiley +2 more sources
Platelets, 2020 Despite the publication in 2009 of a paper on ‘terms and definitions of immune thrombocytopenia’ (ITP), some unresolved issues remain and are reflected by the disagreement in the treatment suggested for primary ITP in adults.
Lorenzo Cirasino +12 more
doaj +1 more source
Older Adults and Immune Thrombocytopenia: Considerations for the Clinician
Clinical Interventions in Aging, 2023 Etienne Crickx,1,2 Matthieu Mahévas,1,3,4 Marc Michel,1 Bertrand Godeau1 1Service de Médecine Interne, Centre national de référence des cytopénies auto-immunes de l’adulte, Hôpital Henri Mondor, Fédération Hospitalo-Universitaire TRUE InnovaTive theRapy ...
Crickx E, Mahévas M, Michel M, Godeau B
doaj
Lenalidomide-Associated ITP [PDF]
Case Reports in Hematology, 2011 Lenalidomide is a potent immunomodulatory agent being used increasingly for treatment of hematologic malignancies including multiple myeloma and myelodysplasia. The common toxicities of lenalidomide, including dose-limiting myelosuppression, are well described.
Christina I. Herold +2 more
openaire +3 more sources
Splenectomy in immune thrombocytopenia: a multicentric retrospective study on predictive factors of response [PDF]
, 2023 openPresupposti dello studio. La trombocitopenia immune (ITP) è una rara malattia ematologica acquisita, caratterizzata dalla distruzione immuno-mediata delle piastrine.
DE CRESCENZO, ANDREA
core
Idiopathic thrombocytopenic purpura (ITP) – new era for an old disease
Romanian Journal of Internal Medicine, 2019 Immune thrombocytopenia is an autoimmune hematological disorder characterized by severely decreased platelet count of peripheral cause: platelet destruction via antiplatelet antibodies which may also affect marrow megakaryocytes.
Onisâi Minodora +4 more
doaj +1 more source